Recruiting

Blood Pressure Management

Sponsor:

Jennifer Lewey, MD, MPH

Code:

NCT07209254

Conditions

Hypertension, Pregnancy Induced

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

High-touch blood pressure management

Low-touch blood pressure management

Study Details

Brief summary:

A multicenter randomized trial that will compare the effectiveness of two postpartum blood pressure (BP) management strategies in improving blood pressure and cardiac function and increasing patient engagement and feeling of control over one's health

Conditions

Hypertension, Pregnancy Induced

Study ID

NCT07209254

Start date

Mar 2, 2026

Status verified date

Apr, 2026

Completion date

Nov, 2029

Anticipated

Primary completion date

Oct, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age ≥18 years
  • Delivery within 14 days
  • Diagnosis of preeclampsia or gestational hypertension with or without severe features during pregnancy or within 14 days postpartum
  • Initiation of blood pressure medication prior to hospital discharge and up to 14 days postpartum
  • English or Spanish speaking (able to read/understand consent and instructions)
  • Has phone texting capabilities

Exclusion Criteria:

  • Diagnosis of chronic hypertension prior to delivery (would therefore include super imposed preeclampsia)
  • Pre-existing cardiovascular disease (including prior myocardial infarction, stroke, heart failure with reduced ejection fraction, ventricular tachycardia, prior cardiac arrest, pacemaker, severe valvular heart disease, or prior cardiac surgery)
  • Chronic kidney disease (stage 3 or higher)
  • Using ≥3 BP medications at time of enrollment

Study Design

Enrollment

770 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: High-touch blood pressure management

experimental: Low-touch blood pressure management

Interventions

High-touch blood pressure management

Twelve weeks of text-based home blood pressure monitoring with BP self-management and team-based care

Low-touch blood pressure management

10 days of text-based home blood pressure monitoring

Primary outcome measure

  • Mean diastolic blood pressure (DBP) [ Time Frame: 12 months postpartum ]

Central Contacts and Locations

Central contacts

Jennifer Lewey, MD, MPH

215-662-7700Jennifer.Lewey@pennmedicine.upenn.edu

Alexis Giron, M.S

Alexis.Giron@Pennmedicine.upenn.edu

Locations

NYU Langone Health

Recruiting

New York, New York, United States, 10022

Contacts

Christina Penfield, MD, MPH

(646)-754-2700christina.penfield@nyulangone.org

Michelle Rojas

(646) 679-0737smart-bp@nyulangone.org

Principal Investigator:

Christina Penfield, MD, MPH

University of Pennsylvania

Recruiting

Philadelphia, Pennsylvania, United States, 19104

Contacts

Alexis Giron, M.S

215-275-2507Alexis.Giron@Pennmedicine.upenn.edu

Principal Investigator:

Jennifer Lewey, MD, MPH

More Information

Sponsor

Jennifer Lewey, MD, MPH

Last update posted

May 22, 2026

Last verified

Apr, 2026

Keywords

  • Postpartum Hypertension
  • Blood pressure management
  • Preeclampsia
  • Hypertension, pregnancy induced

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Jennifer Lewey, MD, MPH on 2026-05-22.