Recruiting

Observational Study

Sponsor:

Memorial Sloan Kettering Cancer Center

Code:

NCT07212166

Conditions

Adolescents and Young Adults With Cancer

Eligibility Criteria

Sex: All

Age: 15 - 39

Healthy Volunteers: Not accepted

Interventions

Patient-Reported Outcome Surveys

Spanish version of PRO-AYA and the cognitive interview

Study Details

Brief summary:

The purpose of this study is to evaluate a questionnaire called PRO-AYA: Patient-Reported Outcomes for Adolescents and Young Adults.

Conditions

Adolescents and Young Adults With Cancer

Study ID

NCT07212166

Start date

Sep 30, 2025

Status verified date

Aug, 2026

Completion date

Sep 30, 2027

Anticipated

Primary completion date

Sep 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 15 - 39

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • English- or Spanish proficient

o As assessed by two items: How well do you speak English? What is your preferred language for healthcare?
  • Between the ages of 15-39
  • Diagnosed with cancer or the recurrence of a cancer as per clinician report and/or received active treatment for cancer between the ages of 15-39
  • Able to complete questionnaires by themselves or with assistance as per self-report
  • For Cohort 1 ONLY:

  • 3 months from last treatment without plan to initiate any form of cancer-directed treatment in the next 3 months OR
  • On chronic cancer-directed therapy for the last 3 months without plan to change cancer-directed therapy in the next 3 months AND
  • ECOG Performance Status (0-4) or KPS/Lansky Score (0-100)

Study Design

Enrollment

120 participants

Anticipated

Interventions and Outcome Measures

Arms

AYAs with cancer who are at least three months post treatment with no additional treatment planned

Complete via REDCap (at enrollment): PRO-AYA (PRO-AYA - Patient-Reported Outcomes for Adolescents and Young Adults), Patient-Reported ECOG PS, EORTC QLQ-C30, Demographic/Clinical Characteristics, Complete via REDCap (7-10 days later):

PRO-AYA, Patient-Reported, ECOG PS

AYAs(Adolescents and Young Adults) who are fluent or prefer their healthcare be delivered in Spanish

Round 1 Cognitive Interviews Complete via REDCap: Spanish PRO-AYA, Demographic/Clinical Characteristic, Item modification based on patient feedback, Cohort 2b (n = 10) (AYAs who prefer healthcare delivery in Spanish) Round 2 Cognitive interviews, Complete via REDCap: Revised Spanish PRO-AYA, Demographic/Clinical Characteristics

Interventions

Patient-Reported Outcome Surveys

PRO-AYA , Patient-Reported ECOG PS, EORTC QLQ-C30, Demographic/Clinical Characteristics

Spanish version of PRO-AYA and the cognitive interview

Revised Spanish PRO-AYA, Demographic/Clinical Characteristics

Primary outcome measure

  • Test-retest reliability [ Time Frame: up to one month ]
  • Linguistically validate PRO-AYA or patients who prefer their healthcare be delivered in Spanish. (Cohort 2) [ Time Frame: up to a month ]

Central Contacts and Locations

Central contacts

Thomas Atkinson, PhD

646-888-0089atkinsot@mskcc.org

Marie Barnett, PhD

646-608-8206

Locations

Memorial Sloan Kettering Basking Ridge (Consent Only)

Recruiting

Basking Ridge, New Jersey, United States, 07920

Contacts

Thomas Atkinson, PhD

646-888-0089

Memorial Sloan Kettering Monmouth (Consent Only)

Recruiting

Middletown, New Jersey, United States, 07748

Contacts

Thomas Atkinson, PhD

646-888-0089

Memorial Sloan Kettering Bergen (Consent Only)

Recruiting

Montvale, New Jersey, United States, 07645

Contacts

Thomas Atkinson, PhD

646-888-0089

Memorial Sloan Kettering Commack (Consent Only)

Recruiting

Commack, New York, United States, 11725

Contacts

Thomas Atkinson, PhD

646-888-0089

Memorial Sloan Kettering Westchester (Consent Only)

Recruiting

Harrison, New York, United States, 10604

Contacts

Thomas Atkinson, PhD

646-888-0089

Memorial Sloan Kettering Cancer Center

Recruiting

New York, New York, United States, 10065

Contacts

Thomas Atkinson, PhD

646-888-0089

Memorial Sloan Kettering Nassau (Consent Only)

Recruiting

Uniondale, New York, United States, 11553

Contacts

Thomas Atkinson, PhD

646-888-0089

More Information

Sponsor

Memorial Sloan Kettering Cancer Center

Last update posted

Aug 4, 2026

Last verified

Aug, 2026

Keywords

  • PRO-AYA: Patient-Reported Outcomes for Adolescents and Young Adults
  • Psychometric and Linguistic Validation

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Memorial Sloan Kettering Cancer Center on 2026-08-04.