Recruiting

Virtual Reality

Sponsor:

Ohio State University Comprehensive Cancer Center

Code:

NCT07216534

Conditions

Hematopoietic and Lymphatic System Neoplasm

Malignant Solid Neoplasm

Psychiatric Disorder

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Survey Administration

Virtual Technology Intervention

Virtual Technology Intervention

Virtual Technology Intervention

Study Details

Brief summary:

This clinical trial compares virtual reality viewing of an unaltered streetscape versus a digitally manipulated opposite streetscape to assess the psychosocial response in participants. Visible measures of neighborhood factors might be associated with health outcomes and risk factors of those outcomes. Short-term exposure to virtual reality environments representing very high or very low levels of neighborhood physical disorder - presence or absence of garbage/litter, presence or absence of graffiti, presence or absence of an abandoned building, presence or absence of large dumpsters, poor or very well-kept building conditions, poor or very well-kept yard conditions, poor or very well-kept road verge conditions may be a safe and effective way to assess psychosocial response in participants.

Conditions

Hematopoietic and Lymphatic System Neoplasm

Malignant Solid Neoplasm

Psychiatric Disorder

Study ID

NCT07216534

Start date

Sep 1, 2026

Status verified date

Jun, 2026

Completion date

Dec 31, 2026

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Adults 18+
  • Must currently live (4+ night/week) at the residence being studied. Only one resident per household will be selected
  • Must understand and be able to read English
  • Must agree to have residence photographed
  • Must be able to wear a VR head mounted display
  • Must live in neighborhood that has been selected for study
  • Must be willing and able to attend an approximately 2 hour in-person visit on Ohio State University (OSU) campus

Exclusion Criteria:

  • Pregnant women
  • Visual or mobility impairment
  • Cannot have epilepsy or other condition that would inhibit them from being able to use a VR headset

Study Design

Enrollment

32 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Arm I (twin followed by opposite streetscape)

Participants have their streetscape photographed. Participants view a standard residential streetscape using VR for up to 5 minutes. Patients then view a digital twin of their streetscape with identical physical disorder using VR for up to 5 minutes followed by viewing their streetscape with the opposite physical disorder using VR for up to 5 minutes.

experimental: Arm II (opposite followed by twin streetscape)

Participants have their streetscape photographed. Participants view a standard residential streetscape using VR for up to 5 minutes. Patients then view their streetscape with the opposite physical disorder using VR for up to 5 minutes followed by viewing a digital twin of their streetscape with identical physical disorder using VR for up to 5 minutes.

Interventions

Survey Administration

Ancillary studies

Virtual Technology Intervention

View standard streetscape

Virtual Technology Intervention

View digital twin of streetscape

Virtual Technology Intervention

View opposite digital streetscape

Primary outcome measure

  • Change in heart rate variability [ Time Frame: From baseline to completion of virtual reality (VR) viewings, up to 1 day ]
  • Change in skin conductance [ Time Frame: From baseline to completion of VR viewings, up to 1 day ]
  • Affective reaction [ Time Frame: After completion of VR viewings, up to 1 day ]
  • Anxiety [ Time Frame: After completion of VR viewings, up to 1 day ]
  • Participant reported discomfort [ Time Frame: After completion of VR viewings, up to 1 day ]

Central Contacts and Locations

Central contacts

The Ohio State University Comprehensive Cancer Center

800-293-5066OSUCCCClinicaltrials@osumc.edu

Locations

Ohio State University Comprehensive Cancer Center

Recruiting

Columbus, Ohio, United States, 43210

Contacts

Jesse Plascak, PhD, MPH

614-293-8024

Principal Investigator:

Jesse Plascak, PhD, MPH

More Information

Sponsor

Ohio State University Comprehensive Cancer Center

Last update posted

Jun 22, 2026

Last verified

Jun, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Ohio State University Comprehensive Cancer Center on 2026-06-22.