Recruiting

Structured Breathing

Sponsor:

Mayo Clinic

Code:

NCT07218458

Conditions

Burnout, Healthcare Workers

Breathing Exercises

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Interventions

Structured Breathing

Study Details

Brief summary:

The purpose of this study is to assess the immediate and long-term effects of structured breathing on clinical symptoms related to mental health including anxiety, depression, perceived stress, and sleep quality.

Conditions

Burnout, Healthcare Workers

Breathing Exercises

Study ID

NCT07218458

Start date

Oct 27, 2025

Status verified date

Apr, 2026

Completion date

Nov 30, 2026

Anticipated

Primary completion date

Sep 30, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Participants must be healthcare professionals at the above-mentioned 4 MCHS sites (Eau Claire, La Crosse, Mankato, Albert Lea).
  • Must score ≥40 on Copenhagen Burnout Inventory Q1-6.
  • Participants must be physically fit enough to perform light exercise.
  • Participants should read and understand English well enough to consent, complete measures, and follow instructions.
  • Participants must have access to a smartphone or tablet.

Exclusion Criteria:

  • Active primary psychotic disorder or substance use disorder (except nicotine dependence) within the past year.
  • Severe or unstable medical condition that could interfere with participation or data collection.
  • Active neurological condition (including seizure disorder, traumatic brain injury, or stroke) that could affect cognitive functioning or brain imaging results.
  • Chronic lung disease (e.g., COPD, cystic fibrosis) or aneurysm.
  • Current pregnancy or planning to become pregnant during the study period

Study Design

Enrollment

40 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Breathing Intervention

Engaging in self-guided breathing sessions to improve brain circulation and mental well-being.

Interventions

Structured Breathing

15, 30, or 36 minute structured breathing sessions based on personal skill level.

Primary outcome measure

  • Assess feasibility of the structured breathing-based intervention among healthcare professionals via ease of recruitment [ Time Frame: Enrollment to end of study participation at 4 months. ]
  • Assess feasibility of the structured breathing-based intervention among healthcare professionals via retention statistics [ Time Frame: Enrollment to end of study participation at 4 months ]
  • Assess feasibility of the structured breathing-based intervention among healthcare professionals via mobile app engagement metrics [ Time Frame: Enrollment to end of study participation at 4 months ]
  • Assess feasibility of structured breathing-based intervention among healthcare professionals via Feasibility of Intervention Measure [ Time Frame: Enrollment to end of study participation at 4 months ]
  • Assess appropriateness of structured breathing-based intervention among healthcare professionals [ Time Frame: Enrollment to end of study participation at 4 months ]
  • Assess acceptability of structured breathing-based intervention among healthcare professionals [ Time Frame: From enrollment to the end of study participation at 4 months ]
  • Assess participant satisfaction related to breathing-based intervention [ Time Frame: Enrollment to end of study participation at 4 months. ]

Central Contacts and Locations

Central contacts

Danielle Boos

715-464-8173boos.danielle@mayo.edu

Paul Min, PhD

507-255-2814min.paul@mayo.edu

Locations

Mayo Clinic Health System-Eau Claire Clinic

Recruiting

Eau Claire, Wisconsin, United States, 54703

Contacts

Danielle Boos

715-464-8173boos.danielle@mayo.edu

Pravesh Sharma, MD

sharma.pravesh@mayo.edu

Principal Investigator:

Pravesh Sharma

More Information

Sponsor

Mayo Clinic

Last update posted

May 5, 2026

Last verified

Apr, 2026

Keywords

  • burnout
  • breathing

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-05-05.