Sponsor:
GlaxoSmithKline
Code:
NCT07218926
Conditions
Gastrointestinal Neoplasms
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
IDRX-42
Sunitinib
Brief summary:
Conditions
Gastrointestinal Neoplasms
Study ID
NCT07218926
Start date
Dec 3, 2025
Status verified date
Sep, 2026
Completion date
Nov 29, 2030
Anticipated
Primary completion date
May 30, 2028
Anticipated
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Enrollment
450 participants
Anticipated
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary purpose
Treatment
Arms
experimental: IDRX-42 (GSK6042981)
active comparator: Sunitinib
Interventions
IDRX-42
Sunitinib
Primary outcome measure
Central contacts
Locations
GSK Investigational Site
Recruiting
Phoenix, Arizona, United States, 85054
Contacts
Principal Investigator:
Mahesh Seetharam
GSK Investigational Site
Recruiting
Duarte, California, United States, 91010
Contacts
Principal Investigator:
Lee Cranmer
GSK Investigational Site
Recruiting
La Jolla, California, United States, 92093-1503
Contacts
Principal Investigator:
Adam Burgoyne
GSK Investigational Site
Recruiting
Los Angeles, California, United States, 90048-1804
Contacts
Principal Investigator:
James Hu
GSK Investigational Site
Recruiting
San Francisco, California, United States, 94158
Contacts
Principal Investigator:
Brian Schulte
GSK Investigational Site
Recruiting
Santa Monica, California, United States, 90404-2023
Contacts
Principal Investigator:
Arun Singh
GSK Investigational Site
Recruiting
Upland, California, United States, 91786-4952
Contacts
Principal Investigator:
Lee Cranmer
GSK Investigational Site
Recruiting
Aurora, Colorado, United States, 80045-2517
Contacts
Principal Investigator:
Breelyn Wilky
GSK Investigational Site
Recruiting
New Haven, Connecticut, United States, 06520
Contacts
Principal Investigator:
Philippos Costa
GSK Investigational Site
Recruiting
Washington D.C., District of Columbia, United States, 20016-2633
Contacts
Principal Investigator:
christian meyer
GSK Investigational Site
Recruiting
Jacksonville, Florida, United States, 41076
Contacts
Principal Investigator:
Steven Attia
GSK Investigational Site
Recruiting
Miami, Florida, United States, 33136
Contacts
Principal Investigator:
Jonathan Trent
GSK Investigational Site
Recruiting
Orlando, Florida, United States, 32806
Contacts
Principal Investigator:
Jacobo Hincapie-Echeverri
GSK Investigational Site
Recruiting
Tampa, Florida, United States, 33612
Contacts
Principal Investigator:
Mauricio Ribeiro
GSK Investigational Site
Recruiting
Chicago, Illinois, United States, 60611
Contacts
Principal Investigator:
Pedro Viveiros
GSK Investigational Site
Recruiting
Chicago, Illinois, United States, 60637
Contacts
Principal Investigator:
Janet Chin
GSK Investigational Site
Recruiting
Iowa City, Iowa, United States, 52242
Contacts
Principal Investigator:
John Rieth
GSK Investigational Site
Recruiting
Overland Park, Kansas, United States, 66210
Contacts
Principal Investigator:
Benjamin Powers
GSK Investigational Site
Recruiting
Baton Rouge, Louisiana, United States, 70808
Contacts
Principal Investigator:
marshall stagg
GSK Investigational Site
Recruiting
Baltimore, Maryland, United States, 21287
Contacts
Principal Investigator:
christian meyer
GSK Investigational Site
Recruiting
Boston, Massachusetts, United States, 02114-2696
Contacts
Principal Investigator:
Edwin Choy
GSK Investigational Site
Recruiting
Boston, Massachusetts, United States, 02215
Contacts
Principal Investigator:
Suzanne George
GSK Investigational Site
Recruiting
Ann Arbor, Michigan, United States, 48109
Contacts
Principal Investigator:
Scott Schuetze
GSK Investigational Site
Recruiting
Rochester, Minnesota, United States, 55905-0001
Contacts
Principal Investigator:
Thanh Ho
GSK Investigational Site
Recruiting
St Louis, Missouri, United States, 63108
Contacts
Principal Investigator:
Mia Weiss
GSK Investigational Site
Recruiting
Omaha, Nebraska, United States, 68130-2042
Contacts
Principal Investigator:
Kirsten Leu
GSK Investigational Site
Recruiting
New Hyde Park, New York, United States, 11042-1118
Contacts
Principal Investigator:
Tony Philip
GSK Investigational Site
Recruiting
New York, New York, United States, 10032-3747
Contacts
Principal Investigator:
Lanyi Chen
GSK Investigational Site
Recruiting
New York, New York, United States, 10065-6007
Contacts
Principal Investigator:
Ciara Kelly
GSK Investigational Site
Recruiting
Rochester, New York, United States, 14642
Contacts
Principal Investigator:
Adrienne Victor
GSK Investigational Site
Recruiting
Charlotte, North Carolina, United States, 28204
Contacts
Principal Investigator:
Johann Hsu
GSK Investigational Site
Recruiting
Durham, North Carolina, United States, 27710
Contacts
Principal Investigator:
Juneko Grilley-Olson
GSK Investigational Site
Recruiting
Canton, Ohio, United States, 44718
Contacts
Principal Investigator:
Nashat Gabrail
GSK Investigational Site
Recruiting
Columbus, Ohio, United States, 43210
Contacts
Principal Investigator:
Gabriel Tinoco
GSK Investigational Site
Recruiting
Portland, Oregon, United States, 97239-3011
Contacts
Principal Investigator:
Michael Heinrich
GSK Investigational Site
Recruiting
Philadelphia, Pennsylvania, United States, 19106
Contacts
Principal Investigator:
Daniel Lefler
GSK Investigational Site
Recruiting
Philadelphia, Pennsylvania, United States, 19111
Contacts
Principal Investigator:
Margaret Mehren
GSK Investigational Site
Recruiting
Pittsburgh, Pennsylvania, United States, 15232
Contacts
Principal Investigator:
Melissa Burgess
GSK Investigational Site
Recruiting
Spartanburg, South Carolina, United States, 29307
Contacts
Principal Investigator:
Ki Young Chung
GSK Investigational Site
Recruiting
Knoxville, Tennessee, United States, 37920
Contacts
Principal Investigator:
Saikrishna Gadde
GSK Investigational Site
Recruiting
Dallas, Texas, United States, 75246
Contacts
Principal Investigator:
Laith Abushahin
GSK Investigational Site
Recruiting
Houston, Texas, United States, 77030
Contacts
Principal Investigator:
Neeta Somaiah
GSK Investigational Site
Recruiting
Salt Lake City, Utah, United States, 84106
Contacts
Principal Investigator:
Stephan Kendall
GSK Investigational Site
Recruiting
Charlottesville, Virginia, United States, 22908-0817
Contacts
Principal Investigator:
Matthew Reilley
GSK Investigational Site
Recruiting
Fairfax, Virginia, United States, 22031
Contacts
Principal Investigator:
Chao Yin
GSK Investigational Site
Recruiting
Richmond, Virginia, United States, 23298-5017
Contacts
Principal Investigator:
Hyun Lee
GSK Investigational Site
Recruiting
Seattle, Washington, United States, 98109-4405
Contacts
Principal Investigator:
Min Park
GSK Investigational Site
Recruiting
Tacoma, Washington, United States, 98405
Contacts
Principal Investigator:
Katherine Martin
GSK Investigational Site
Recruiting
Milwaukee, Wisconsin, United States, 53226
Contacts
Principal Investigator:
John Charlson
GSK Investigational Site
Recruiting
Calgary, Alberta, Canada, T2N 5G2
Contacts
Principal Investigator:
Xiaolan Feng
GSK Investigational Site
Recruiting
Toronto, Ontario, Canada, M5G 2M9
Contacts
Principal Investigator:
Albiruni Abdul Razak
GSK Investigational Site
Recruiting
Montreal, Quebec, Canada, H4A 3J1
Contacts
Principal Investigator:
Jonathan Noujaim
Sponsor
GlaxoSmithKline
Last update posted
Oct 5, 2026
Last verified
Sep, 2026
Keywords
Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-23. This information was provided to ClinicalTrials.gov by GlaxoSmithKline on 2026-10-05. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.