Recruiting

Behavioral ActivationPeer-Delivered Behavioral Activation in a CCBHC

Sponsor:

Wayne State University

Code:

NCT07219394

Conditions

Major Depressive Disorder

Substance Use Disorders

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Peer Activate

Peer-delivered non-specific services

Study Details

Brief summary:

Low-income individuals have limited access to evidence-based interventions for mental health. Peer recovery specialists, individuals in recovery from mental health and/or substance use problems, have the potential to increase access to evidence-based interventions for individuals from low-resource communities, particularly when trained and supervised in models that are acceptable and feasible in these communities. This study will examine the effectiveness and implementation potential of a peer-delivered evidence-based intervention (Behavioral Activation) among individuals receiving services from a community-based treatment setting providing integrated physical and behavioral healthcare.

Conditions

Major Depressive Disorder

Substance Use Disorders

Study ID

NCT07219394

Start date

May 1, 2026

Status verified date

Apr, 2026

Completion date

Jan 15, 2029

Anticipated

Primary completion date

Jan 15, 2029

Anticipated

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

Age 18 years old or older
Report clinically-significant symptoms of depression, as indexed by a score of 8+ on the PHQ-9.

Exclusion Criteria:

Active, under treated psychotic symptoms or mania that would interfere with participation in study procedures
Inability to provide informed consent and/or complete procedures in English

Study Design

Enrollment

250 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Behavioral Activation

Peer Activate is an adapted behavioral activation (BA) intervention, developed for delivery by peer recovery specialists to reduce rates of depressive symptoms and substance use. BA focuses on increasing positive reinforcement through engaging in adaptive, valued behaviors. BA has been found to be effective in improving substance use outcomes and decreasing depressive symptoms among low-income individuals with SUD. Peer Activate includes 6 weekly sessions with up to 6 additional booster sessions.

active comparator: Enhanced Treatment as Usual

Enhanced treatment as usual (ETAU) involves peer-delivered non-directive support, including facilitated linkages to care and non evidence-based intervention approaches typically used by peer recovery specialists.

Interventions

Peer Activate

Peer-delivered non-specific services

Peers will deliver non-specific peer services, including linkage to care, general support, and facilitated referrals to external providers as needed.

Primary outcome measure

Change in Hamilton Depression Rating Scale [ Time Frame: Baseline, post-intervention (approximately 3 months after baseline), 6- and 12-month follow-up ]

Central Contacts and Locations

Central contacts

Julia Felton, PhD

7049957832 hv8914@wayne.edu

Locations

Detroit Recovery Project

Recruiting

Detroit, Michigan, United States, 48208

More Information

Sponsor

Wayne State University

Last update posted

Apr 17, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Wayne State University on 2026-04-17.