Recruiting

Integrative Care

Sponsor:

Veterans Medical Research Foundation

Code:

NCT07220681

Conditions

Posttraumatic Stress Disorder (PTSD)

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Yoga and meditation

Wellness

Positive affect

Information

Study Details

Brief summary:

The goal of this clinical trial is to determine whether which types of integrative care, meaning a combination of psychotherapy and mind-body interventions, lead to the most changes in functioning among Veterans with posttraumatic stress disorder (PTSD). The main aims are:

1. To evaluate the impact of integrative care approaches on functional outcomes among Veterans with PTSD.
2. To examine factors relevant to the implementation of integrated treatments for PTSD from the perspective of patients, providers and administrators in the VA Healthcare System.

Participants will:

1. Complete assessments at the beginning of the study and 12- and 24-weeks later.
2. Engage in 12 weeks of integrated care, with the type being randomly assigned.

Conditions

Posttraumatic Stress Disorder (PTSD)

Study ID

NCT07220681

Start date

Apr 23, 2026

Status verified date

Apr, 2026

Completion date

Sep 30, 2029

Anticipated

Primary completion date

Jun 30, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • clinical diagnosis
  • eligibility for Cognitive Processing Therapy (CPT) at a participating VA site
  • able to consent to study activities

Exclusion Criteria:

  • current, active engagement in one of the included approaches (per clinician judgment)
  • medical conditions that contraindicate engaging in the experimental interventions

Study Design

Enrollment

300 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Usual care

Information about local and national complementary and integrative health programs

experimental: Yoga and meditation

Hatha yoga classes via videoconferencing and self-learning of Mantram Repetition Program

experimental: Wellness

Weekly exercise/nutrition classes to support lifestyle changes

experimental: Positive affect

Weekly classes focused on increasing positive affect and social support

Interventions

Yoga and meditation

12 weekly 60-minute hatha yoga classes and access to video-based training in a portable mantra-based meditation practice

Wellness

12 weekly 60-minute classes to provide education about exercise and nutrition and facilitate lifestyle changes

Positive affect

12 weekly 60-minute classes to teach strategies for increasing positive affect and to provide social connection

Information

Provision of written information about local and national complementary and integrative care resources

Primary outcome measure

  • Inventory of Psychosocial Functioning (IPF) [ Time Frame: weeks 0, 12 and 24 ]

Central Contacts and Locations

Central contacts

Ariel J Lang, PhD, MPH

858-552-8585ariel.lang@va.gov

Haley Suit, MA

haley.suit@va.gov

Locations

VA San Diego Healthcare System

Recruiting

San Diego, California, United States, 92161

Contacts

Ariel J Lang, PhD, MPH

8585528585ariel.lang@va.gov

Edith Bonilla, MSW

edith.bonilla@va.gov

VA Portland Healthcare System

Recruiting

Portland, Oregon, United States, 97239-2964

Contacts

Maya O'Neil, PhD

503-220-8262maya.oneil@va.gov

VA North Texas Healthcare System

Recruiting

Dallas, Texas, United States, 75216-7167

Contacts

Bella Etingen, PhD

bella.etingen@va.gov

More Information

Sponsor

Veterans Medical Research Foundation

Last update posted

Jun 12, 2026

Last verified

Apr, 2026

Keywords

  • PTSD
  • complementary and integrative health
  • Veterans
  • implementation

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Veterans Medical Research Foundation on 2026-06-12.