Recruiting

Observational Study

Sponsor:

Stanford University

Code:

NCT07221643

Conditions

No Condition

Skin Carotenoids and Immune-aging

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Study Details

Brief summary:

This study aims to examine the connection between the level of carotenoids in the skin and a number of immune related health parameters.

Conditions

No Condition

Skin Carotenoids and Immune-aging

Study ID

NCT07221643

Start date

Oct 9, 2025

Status verified date

Oct, 2025

Completion date

Apr 1, 2026

Anticipated

Primary completion date

Mar 1, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Willing and able to provide written informed consent
  • Age 18-30 years OR 65 years and older
  • Healthy individuals without uncontrolled medical conditions (over the counter inhaled and topical steroids allowed)
  • Fiitzpatrick I-VI (all skin types)

Exclusion Criteria:

  • Pregnant or breastfeeding
  • uncontrolled medical conditions
  • Skin conditions on the upper extremity that would interfere with skin measurements of carotenoid levels such as active atopic dermatitis or psoriasis
  • Concurrent use of medications that affect the immune system, within 4 weeks of enrollment (eg. prednisone, biologics, methotrexate, rapamycin, prescription topical steroids, prescription inhaled steroids, others)
  • Unable to follow study protocol

Study Design

Enrollment

40 participants

Anticipated

Interventions and Outcome Measures

Arms

Young adult

Participants are 18 to 30 years old.

Older adult

Participants are over 65 years old.

Primary outcome measure

  • Skin carotenoid levels and skin aging features [ Time Frame: one day ]

Central Contacts and Locations

Central contacts

Xiaochen Zhong, BA

408-816-0111xczhong@stanford.edu

Po-Han Ho, MD

pohanho@stanford.edu

Locations

Stanford Health - General Dermatology Clinic

Recruiting

Redwood City, California, United States, 94063

Principal Investigator:

Anne Lynn S. Chang, MD

More Information

Sponsor

Stanford University

Last update posted

Dec 15, 2025

Last verified

Oct, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Stanford University on 2025-12-15.