Recruiting

LAM Nerve Block

Sponsor:

University of Washington

Code:

NCT07221903

Conditions

Regional Anesthesia

Burn

Skin Grafting

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

Skin donor sites in patients undergoing split-thickness skin grafting surgeries can be very painful postoperatively. This site is most often the anterolateral thigh, the pain at which location can traditionally be covered by a fascia iliaca nerve block, although that comes with the disadvantage of losing motor functions in the femoral nerve distribution. The LAM nerve block, which is relatively new, aims to provide analgesia in the distribution of the lateral and anterior femoral cutaneous nerves. In short, this nerve block would decrease the sensation of the anterolateral thigh area without affecting the motor function of the leg. Investigators aim to study the consistency and coverage size of sensation changes by mapping out the area after the block in each patient.

Conditions

Regional Anesthesia

Burn

Skin Grafting

Study ID

NCT07221903

Start date

Oct 22, 2025

Status verified date

Oct, 2025

Completion date

Dec 31, 2026

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. 18 years or older
2. Scheduled surgery for STSG w/ donor site coming from thigh
3. Care team requests LAM nerve block
4. Anticipated postop pain in the cutaneous areas of anterior and lateral thigh

Exclusion Criteria:
5. Inability to communicate sensation or motor changes in their body
6. Preexisting sensory or motor deficits in the femoral nerve distribution
7. Contraindication to the medication used or a peripheral nerve block, such as allergy to amide local anesthetics, severe liver dysfunction, injection site infection etc
8. Pregnancy
9. Prisoners
10. Non-English Speaking/reading
11. Surgeries with anticipated or actual duration of 6 hours or longer
12. TBSA 20% or greater
13. Severe distracting injuries/polytrauma (e.g., large or significant bone fractures)

Study Design

Enrollment

10 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Area of sensory change after nerve block [ Time Frame: 20 min after nerve block placement ]

Central Contacts and Locations

Central contacts

Adrienne James

206-744-4634ajames1@uw.edu

Locations

Harborview Medical Center

Recruiting

Seattle, Washington, United States, 98104

More Information

Sponsor

University of Washington

Last update posted

Nov 4, 2025

Last verified

Oct, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Washington on 2025-11-04.