Recruiting

Tinted Contact Lenses

Sponsor:

University of Alabama at Birmingham

Code:

NCT07223086

Conditions

Concussion, Mild

Photophobia

Contact Lens

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Narrow band (tinted) contact lenses

broad band (clear) contact lenses

Study Details

Brief summary:

The purpose of this study is to gather pilot data on the effectiveness of daily disposable tinted contact lenses in reducing photophobia (light sensitivity) following a concussion, with the goal of facilitating the return to work or school.

Conditions

Concussion, Mild

Photophobia

Contact Lens

Study ID

NCT07223086

Start date

May 8, 2026

Status verified date

Jun, 2026

Completion date

Apr 1, 2027

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • diagnosed mild traumatic brain injury (concussion)
  • age 18 or older
  • Within 24 months of initial injury
  • experiencing symptoms of photophobia (light sensitivity), increased photophobia since the injury, or no symptoms of photophobia

Exclusion Criteria:

  • moderate or severe concussion
  • active infection or inflammation that contradicts the use of soft contact lenses
  • subjects unable to safely perform insertion and removal of the contact lenses

Study Design

Enrollment

60 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Participants with concussion and light sensitivity fit with broad band (clear) contact lens

UPSIS-2 scale 15-60, eligible participants score greater than or equal to 26 are fit in broad band (clear) contact lenses.

active comparator: Participants with concussion and light sensitivity fit with narrow band (tinted) contact lens

UPSIS-2 scale 15-60, eligible participants score greater than or equal to 26 are fit in narrow wavelength (tinted) contact lenses.

Interventions

Narrow band (tinted) contact lenses

Participants will receive these contacts based on the results of the Utah Photophobia Symptom Impact Scale (survey).

broad band (clear) contact lenses

Participants will receive these contacts based on the results of the Utah Photophobia Symptom Impact Scale (survey).

Primary outcome measure

  • Number of participants that improved symptoms of light sensitivity with narrow band (tinted) contact lenses [ Time Frame: Baseline, 1 week ]

Central Contacts and Locations

Central contacts

Candice I Turner, OD

(205)934-0997citurner@uab.edu

Katherine K Weise, OD

(205) 934-6758kweise@uab.edu

Locations

UAB Eye Care

Recruiting

Birmingham, Alabama, United States, 35294

Contacts

Candice I Turner, OD

(205)934-0997citurner@uab.edu

Katherine K Weise, OD

(205) 934-6758kweise@uab.edu

Principal Investigator:

Candice I Turner, OD

More Information

Sponsor

University of Alabama at Birmingham

Last update posted

Jun 11, 2026

Last verified

Jun, 2026

Keywords

  • Mild concussion
  • tinted contact lenses
  • light sensitivity

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Alabama at Birmingham on 2026-06-11.