Recruiting

Observational Study

Sponsor:

Yale University

Code:

NCT07224204

Conditions

Cancer

Adolescent Cancer

Young Adult Cancer

Eligibility Criteria

Sex: All

Age: 13 - 39

Healthy Volunteers: Not accepted

Interventions

Life at 100.4

Study Details

Brief summary:

The purpose of this study is to design and Beta test the Life at 100.4, an immersive social virtual reality education tool, with an anticipated 5 patient-caregiver-provider triads.Patients at Yale Pediatric Hematology and Oncology with a new oncologic diagnosis and their caregivers will be eligible for enrollment. Investigators will determine the feasibility and acceptability of implementing Life at 100.4 using validated measures.

Conditions

Cancer

Adolescent Cancer

Young Adult Cancer

Study ID

NCT07224204

Start date

Feb 11, 2026

Status verified date

Feb, 2026

Completion date

Apr, 2027

Anticipated

Primary completion date

Apr, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 13 - 39

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Newly diagnosed with a malignancy or bone marrow failure condition
  • Planned to receive chemotherapy and receive a central line

Exclusion Criteria:

  • Medical contraindication to virtual reality including head wounds and history of seizure with flashing lights
  • No plan to receive chemotherapy

Study Design

Enrollment

45 participants

Anticipated

Allocation

Non randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

no intervention: Objective 1: Focus groups

Participants will participate in a 45 minute to 1-hour long focus group with similar stake holders to inform the intervention. These groups will take place via Zoom teleconferencing software, have 4-6 participants per group and will be run by appropriately trained study staff.

experimental: Objective 3:

Beta testing of VR-based educational intervention, Life at 100.4, to improve understanding of fever with neutropenia, how and when to check for it, and what to do when they have a fever.

Interventions

Life at 100.4

An Immersive Social Virtual Reality Education Tool, participation up to 2 hours

Primary outcome measure

  • Multimodal Presence Scale for Virtual Environments [ Time Frame: immediately post-intervention, up to 2 hours ]
  • System Usability Scale (SUS) [ Time Frame: immediately post-intervention, up to 2 hours ]
  • Technology Acceptance Model (TAC) [ Time Frame: immediately post-intervention, up to 2 hours ]

Central Contacts and Locations

Central contacts

Asher Marks, MD

203-785-4640asher.marks@yale.edu

Vidya Puthepura, MD

203-785-4640vidya.puthenpura@yale.edu

Locations

Pediatric Hematology/Oncology Clinic in Smilow Cancer Hospital

Recruiting

New Haven, Connecticut, United States, 06520

More Information

Sponsor

Yale University

Last update posted

Feb 25, 2026

Last verified

Feb, 2026

Keywords

  • Adolescent Cancer Patients and Caregivers
  • Young Adult Cancer Patients and Caregivers

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Yale University on 2026-02-25.