Recruiting

DESCANSO/REST

Sponsor:

Memorial Sloan Kettering Cancer Center

Code:

NCT07225088

Conditions

Solid Tumor

Solid Tumor, Adult

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

DESCANSO/Depresión/Depressed Mood, Cansancio/Fatigue, and Sueño/Sleep; Rest in English

Study Details

Brief summary:

The purpose of this study is to improve ways of providing mental health support to Spanish-speaking Latino participants who have cancer and experience depression, insomnia, and fatigue. Investigators will test a special mental health intervention called DESCANSO/REST (Depresión/Depressed Mood, Cansancio/Fatigue, and Sueño/Sleep). The intervention can be delivered through telehealth.

Conditions

Solid Tumor

Solid Tumor, Adult

Study ID

NCT07225088

Start date

Jan 23, 2026

Status verified date

Aug, 2026

Completion date

Apr, 2029

Anticipated

Primary completion date

Apr, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Provider Eligibility Criteria:

Participant eligibility will be determined by a self-report screener. Inclusion Criteria Self-Report Criteria

  • Mental health provider
  • Treats Latino cancer patients and/or survivors
  • Has at least 3 years of clinical experience providing psychosocial services to cancer patients and/or survivors
  • Able to read Spanish determined by the question: "Can you read in Spanish? Yes/No"

Patient Eligibility Criteria:

A patient cannot be considered eligible for this study unless ALL of the following conditions are met. Participant eligibility will be determined by an initial EMR review followed by a self-report screener.

Inclusion Criteria EMR Criteria

  • Documentation of Disease

o Pathologically confirmed solid tumor cancer (either most recent or new diagnosis)
  • Definition of Disease \[or Measurable Disease\]

o Diagnosed with stages I, II, or III
  • Prior Treatment

  • Currently undergoing systemic therapy (chemotherapy, radiation therapy, and/or immunotherapy) or within the first year following completion of systemic therapy Self-Report Criteria
  • Age ≥ 21 years
  • Lives in mainland U.S. or Puerto Rico
  • Identifies as Latino/a or Hispanic
  • Reports Spanish as their preferred language
  • Speaks Spanish "Very well" or "Well" as determined by the question: "How well do you speak Spanish?"
  • Presence of fatigue and disturbed sleep determined by a score of ≥ 3 on the MD Anderson Symptom Inventory

Exclusion Criteria EMR Criteria

o In the judgment of the treating physician, protocol investigators, and/or study staff, presence of cognitive impairment (e.g., delirium or dementia) sufficient to preclude meaningful informed consent and/or study participation

Self-Report Criteria

  • History of comorbidities within the last 12 months associated with fatigue and poor sleep, including hypothyroidism or abnormal thyroid function, sleep apnea, chronic obstructive pulmonary disease, neuromuscular disease, alcohol or drug abuse
  • Pregnant or lactating, women only
  • Presence of suicidal risk determined by any affirmative response on the Columbia-Suicide Severity Rating Scale

Study Design

Enrollment

125 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Experimental Intervention: DESCANSO

Participants will receive DESCANSO (Depresión/Depressed Mood, Cansancio/Fatigue, and Sueño/Sleep; Rest in English)

no intervention: Control Intervention: Enhanced Usual Care

Participants will receive Enhanced Usual Care

Interventions

DESCANSO/Depresión/Depressed Mood, Cansancio/Fatigue, and Sueño/Sleep; Rest in English

DESCANSO (Depresión/Depressed Mood, Cansancio/Fatigue, and Sueño/Sleep; Rest in English)

Primary outcome measure

  • Number of participants who complete at least 5 DESCANSO sessions [ Time Frame: Up to 1 year ]

Central Contacts and Locations

Central contacts

Locations

Memorial Sloan Kettering Cancer Center Basking Ridge (Limited Protocol Activities)

Recruiting

Basking Ridge, New Jersey, United States, 07920

Contacts

Devika Jutagir, PhD

646-888-8361

Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

Recruiting

Middletown, New Jersey, United States, 07748

Contacts

Devika Jutagir, PhD

646-888-8361

Memorial Sloan Kettering Bergen (Limited Protocol Activities)

Recruiting

Montvale, New Jersey, United States, 07645

Contacts

Devika Jutagir, PhD

646-888-8361

Memorial Sloan Kettering Suffolk-Commack (Limited protocol activity)

Recruiting

Commack, New York, United States, 11725

Contacts

Devika Jutagir, PhD

646-888-8361

Memorial Sloan Kettering Westchester (Limited Protocol Activities)

Recruiting

Harrison, New York, United States, 10604

Contacts

Devika Jutagir, PhD

646-888-8361

Memorial Sloan Kettering Cancer Center

Recruiting

New York, New York, United States, 10065

Contacts

Devika Jutagir, PhD

646-888-8361

Principal Investigator:

Devika Jutagir, PhD

Memorial Sloan Kettering Nassau (Limited Protocol Activites)

Recruiting

Rockville Centre, New York, United States, 11553

Contacts

Devika Jutagir, PhD

646-888-8361

More Information

Sponsor

Memorial Sloan Kettering Cancer Center

Last update posted

Aug 12, 2026

Last verified

Aug, 2026

Keywords

  • Solid Tumor
  • Solid Tumor Stage I
  • Solid Tumor Stage II
  • Solid Tumor Stage III
  • Memorial Sloan Kettering Cancer Center
  • 25-277

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Memorial Sloan Kettering Cancer Center on 2026-08-12.