Recruiting

Cannabis

Sponsor:

City of Hope Medical Center

Code:

NCT07225738

Conditions

Multiple Myeloma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Non-Interventional Study

Study Details

Brief summary:

This study assesses the impact of cannabis (also commonly called marijuana, weed, or THC) use on quality of life among patients with multiple myeloma who are receiving chemotherapy. It also evaluates the potential benefits and harms of cannabis use.

Conditions

Multiple Myeloma

Study ID

NCT07225738

Start date

Jan 21, 2026

Status verified date

Feb, 2026

Completion date

Aug 22, 2030

Anticipated

Primary completion date

Aug 22, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • \* Documented informed consent of the participant

  • Age: ≥ 18 years
  • ECOG ≤ 3
  • Ability to read and understand English
  • Patient must be newly diagnosed with a histologically confirmed multiple myeloma
  • Patients may have started first line therapies and received up to four cycles
  • HCP SURVEY: Documented informed consent of the participant
  • HCP SURVEY: Age: ≥ 18 years
  • HCP SURVEY: Licensed physician, physician assistant, nurse practitioner, or registered nurse
  • HCP SURVEY: Currently practicing in oncology or providing direct care to oncology patients
  • HCP SURVEY: Able to read and understand English
  • HCP SURVEY: Affiliation with City of Hope

Exclusion Criteria:

  • \* Patients may not have completed five cycles of first line therapy or undergone any second line therapy

  • Other active malignancy
  • Patients may not have undergone autologous hematopoietic stem cell transplantation
  • Unable to comply with the study assessments
  • HCP SURVEY: Reports directly to study PI (Dr. Richard Lee)
  • HCP SURVEY: Member of the study team or involved in survey design or analysis
  • HCP SURVEY: Individuals with a real or perceived conflict of interest that could bias survey responses

Study Design

Enrollment

700 participants

Anticipated

Interventions and Outcome Measures

Arms

Observational group I

Patients complete surveys and undergo blood sample collection throughout the study.

Observational group II

Healthcare providers complete a survey on study.

Interventions

Non-Interventional Study

Non-interventional study

Primary outcome measure

  • Longitudinal patterns in quality of life [ Time Frame: Up to one year ]
  • Potential therapeutic benefit and adverse effects associated with cannabis use [ Time Frame: Up to one year ]
  • Potential therapeutic benefit and adverse effects associated with cannabis use [ Time Frame: Up to one year ]

Central Contacts and Locations

Locations

City of Hope Medical Center

Recruiting

Duarte, California, United States, 91010

Contacts

Richard T. Lee

949-671-4091RichLee@coh.org

Principal Investigator:

Richard T. Lee

City of Hope at Irvine Lennar

Recruiting

Irvine, California, United States, 92618

Contacts

Richard T. Lee

949-671-4091RichLee@coh.org

Principal Investigator:

Richard T. Lee

More Information

Sponsor

City of Hope Medical Center

Last update posted

Feb 20, 2026

Last verified

Feb, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by City of Hope Medical Center on 2026-02-20.