Recruiting
Phase 1

Acceptance Commitment Therapy

Sponsor:

Texas Tech University

Code:

NCT07239609

Conditions

Depression in Adults

Anxiety Disorder Generalized

Grief

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Acceptance Commitment Therapy

Study Details

Brief summary:

This project aims to implement and evaluate a dyadic intervention (i.e., acceptance commitment therapy) for persons with AD/ADRD and their care partners. We hypothesize the intervention will be feasible, acceptable, and show preliminary efficacy of the dyadic interveniotns.

Conditions

Depression in Adults

Anxiety Disorder Generalized

Grief

Study ID

NCT07239609

Start date

Apr 1, 2026

Status verified date

Nov, 2025

Completion date

Dec 31, 2027

Anticipated

Primary completion date

Oct 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria

Inclusion (person with MCI or MNCD):

  • 18+
  • MMSE= 21-27
  • Able to communicate in English

Inclusion (care partner):

  • 18+
  • Identifies as a care partner of a person with MNCD
  • Able to communicate in English
  • MMSE= 28-30
  • Is a family member or friend of the person with MNCD

Exclusion Criteria

Exclusion (person with MCI or MNCD):

  • Currently in an intervention for reducing anxiety or depression related to their dementia
  • MMSE= 28+ or less than 21

Exclusion (care partner):

  • MMSE= <28
  • Is a formal (paid) caregiver

Study Design

Enrollment

100 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Acceptance Commitment Therapy

Acceptance and Commitment Therapy (ACT) is a form of cognitive-behavioral therapy that aims to enhance psychological flexibility through six core processes: acceptance, cognitive defusion, being present, self-as-context, values clarification, and committed action. Rather than attempting to eliminate difficult thoughts and feelings, ACT encourages individuals to accept them while committing to behavior changes consistent with their personal values.

Interventions

Acceptance Commitment Therapy

Acceptance and Commitment Therapy (ACT) is a form of cognitive-behavioral therapy that aims to enhance psychological flexibility through six core processes: acceptance, cognitive defusion, being present, self-as-context, values clarification, and committed action. Rather than attempting to eliminate difficult thoughts and feelings, ACT encourages individuals to accept them while committing to behavior changes consistent with their personal values.

Primary outcome measure

  • Patient Health Questionnaire-9 [ Time Frame: 6 weeks ]
  • Geriatric Depression Short From [ Time Frame: 6 Weeks ]
  • The Generalized Anxiety Disorder-7 [ Time Frame: 6 weeks ]
  • General Anxiety Scale-10 [ Time Frame: 6 Weeks ]
  • Pre-death grief-12 [ Time Frame: 6 weeks ]

Central Contacts and Locations

Central contacts

Jonathan Singer, Ph.D.

17757228066jonsinge@ttu.edu

Locations

Texas Tech University Plaza Building

Recruiting

Lubbock, Texas, United States, 79409-2051

Contacts

Jonathan Singer, Ph.D.

7757228066jonsinge@ttu.edu

More Information

Sponsor

Texas Tech University

Last update posted

May 15, 2026

Last verified

Nov, 2025

Keywords

  • Mild Cognitive Impariment
  • Mild Neurocognitive Disorder
  • Dyadic intervention

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Texas Tech University on 2026-05-15.