Recruiting

PRN Follow-Up

Sponsor:

Seattle Children's Hospital

Code:

NCT07243652

Conditions

Bronchiolitis Acute

Eligibility Criteria

Sex: All

Age: 0 - 2

Healthy Volunteers: Not accepted

Interventions

Moderate-Resource Implementation Strategy

High-Resource Implementation Strategy

Study Details

Brief summary:

Although automatic follow-up is a nearly universal practice, research has shown that these visits are often unnecessary after hospitalizations caused by bronchiolitis. Despite endorsement by national pediatric authorities, robust evidence, and family enthusiasm for as-needed (PRN) follow-up, it remains substantially underutilized for children hospitalized for bronchiolitis.

The goal of I-DECIDE is to compare the effects of two multi-component implementation strategies, both of which aim to (a) increase PRN follow-up prescribing by hospitalists (physicians who care for hospitalized children) and (b) decrease unnecessary follow-up visit attendance by families.

Conditions

Bronchiolitis Acute

Study ID

NCT07243652

Start date

Nov 1, 2025

Status verified date

Nov, 2025

Completion date

Dec, 2029

Anticipated

Primary completion date

May, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 2

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Primary diagnosis of bronchiolitis, discharged by a generalist inpatient service from a non-ICU, non-emergency department, non-step down unit

Exclusion Criteria:

  • Children with a history of gestational age <28 weeks, chronic lung disease, complex or hemodynamically significant heart disease, immunodeficiency, or neuromuscular disease
  • Children being discharged with home oxygen therapy

Study Design

Enrollment

2700 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Moderate-Resource Implementation Strategy

experimental: High-Resource Implementation Strategy

Interventions

Moderate-Resource Implementation Strategy

The moderate-resource implementation strategy includes educational outreach (including family-facing materials to support follow-up decision making), audit and feedback (review of clinician performance, captured in a structured report), and materials for clinical decision support.

High-Resource Implementation Strategy

The high-resource implementation strategy includes all of the moderate resource components, plus two forms of external facilitation: small-group facilitation and expert clinical decision support coach-led facilitation. In total, the high-resource implementation strategy includes educational outreach (including family-facing materials to support follow-up decision-making), audit and feedback (review of clinician performance, captured in a structured report), materials for clinical decision support, small-group facilitation and expert clinical decision support coach-led facilitation.

Primary outcome measure

  • Adoption [ Time Frame: Within 7 days of hospital discharge ]

Central Contacts and Locations

Central contacts

Eric Coon, MD, MS

206-884-1223Eric.Coon@seattlechildrens.org

Chris Bonafide, MD, MSCE

bonafide@chop.edu

Locations

Children's of Alabama

Recruiting

Birmingham, Alabama, United States, 35233

Phoenix Children's Hospital - Arrowhead Campus

Recruiting

Glendale, Arizona, United States, 85308

Phoenix Children's Hospital

Recruiting

Phoenix, Arizona, United States, 85016

Adventist Health Lodi Memorial

Recruiting

Lodi, California, United States, 95240

Children's Hospital Los Angeles

Recruiting

Los Angeles, California, United States, 90027

Valley Children's Hospital

Recruiting

Madera, California, United States, 93636

Children's Hospital Orange County (CHOC)

Recruiting

Orange, California, United States, 92868

University of California Davis Children's Hospital

Recruiting

Sacramento, California, United States, 95817

Children's Hospital Colorado

Recruiting

Aurora, Colorado, United States, 80045

Connecticut Children's Medical Center

Recruiting

Hartford, Connecticut, United States, 06106

Yale-New Haven Children's Hospital

Recruiting

New Haven, Connecticut, United States, 06511

Children's National Medical Center

Recruiting

Washington D.C., District of Columbia, United States, 20010

Johns Hopkins All Children's Hospital

Recruiting

St. Petersburg, Florida, United States, 33701

Ann & Robert H. Lurie Children's Hospital of Chicago

Recruiting

Chicago, Illinois, United States, 60611

OSF Children's Hospital of Illinois

Recruiting

Peoria, Illinois, United States, 61637

Riley Hospital for Children

Recruiting

Indianapolis, Indiana, United States, 46202

Northern Light Eastern Maine Medical Center

Recruiting

Bangor, Maine, United States, 04401

Johns Hopkins Children's Center

Recruiting

Baltimore, Maryland, United States, 21287

Boston Children's Hospital

Recruiting

Boston, Massachusetts, United States, 02115

Baystate Children's Hospital

Recruiting

Springfield, Massachusetts, United States, 01199

Children's Mercy Kansas City

Recruiting

Kansas City, Missouri, United States, 64108

Cox Medical Center South

Recruiting

Springfield, Missouri, United States, 65807

Bryan Medical Center - Children's Nebraska Community site

Recruiting

Lincoln, Nebraska, United States, 68506

Children's Nebraska

Recruiting

Omaha, Nebraska, United States, 68114

Children's Hospital at Dartmouth-Hitchcock

Recruiting

Manchester, New Hampshire, United States, 03104

JM Sanzari Children's Hospital, Hackensack Meridian Children's Health

Recruiting

Hackensack, New Jersey, United States, 07601

CHOP Pediatric Care at Penn Medicine/Princeton Health

Recruiting

Plainsboro, New Jersey, United States, 08536

Albany Medical Center

Recruiting

Albany, New York, United States, 12208

Oishei Children's Hospital

Recruiting

Buffalo, New York, United States, 14203

Hassenfeld Children's Hospital at NYU Langone

Recruiting

New York, New York, United States, 10016

University of Rochester Golisano Children's Hospital

Recruiting

Rochester, New York, United States, 14642

Children's Hospital at Montefiore

Recruiting

The Bronx, New York, United States, 10467

Wake Forest Baptist Medical Center

Recruiting

Winston-Salem, North Carolina, United States, 27103

Akron Children's Hospital

Recruiting

Akron, Ohio, United States, 44308

Cincinnati Children's Hospital Medical Center

Recruiting

Cincinnati, Ohio, United States, 45229

University Hospitals Rainbow Babies and Children's Hospital

Recruiting

Cleveland, Ohio, United States, 44106

Cleveland Clinic Children's

Recruiting

Cleveland, Ohio, United States, 44195

Nationwide Children's Hospital

Recruiting

Columbus, Ohio, United States, 43205

Dayton Children's Hospital

Recruiting

Dayton, Ohio, United States, 45404

Children's Hospital of Oklahoma

Recruiting

Oklahoma City, Oklahoma, United States, 73104

Children's Hospital of Philadelphia

Recruiting

Philadelphia, Pennsylvania, United States, 19104

UPMC Children's Hospital of Pittsburgh

Recruiting

Pittsburgh, Pennsylvania, United States, 15224

Hasbro Children's Hospital

Recruiting

Providence, Rhode Island, United States, 02903

Texas Children's Hospital - North Campus

Recruiting

Austin, Texas, United States, 78717

Baylor Scott and White Mclane Children's

Recruiting

Belton, Texas, United States, 76513

Children's Memorial Hermann

Recruiting

Houston, Texas, United States, 77030

Texas Children's Hospital - Main

Recruiting

Houston, Texas, United States, 77030

Texas Children's Hosptial - West Campus

Recruiting

Houston, Texas, United States, 77094

Covenant Children's Hospital

Recruiting

Lubbock, Texas, United States, 79410

Texas Children's Hospital The Woodlands

Recruiting

The Woodlands, Texas, United States, 77384

Primary Children's Hospital - Lehi Campus

Recruiting

Lehi, Utah, United States, 84043

Primary Children's Hospital

Recruiting

Salt Lake City, Utah, United States, 84113

Seattle Children's Hospital

Recruiting

Seattle, Washington, United States, 98105

Contacts

Eric Coon

206-884-1223Eric.Coon@seattlechildrens.org

WVU Children's Hospital

Recruiting

Morgantown, West Virginia, United States, 26506

Children's Wisconsin

Recruiting

Milwaukee, Wisconsin, United States, 53226

Children's Wisconsin - Fox Valley

Recruiting

Neenah, Wisconsin, United States, 54956

More Information

Sponsor

Seattle Children's Hospital

Last update posted

Feb 4, 2026

Last verified

Nov, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Seattle Children's Hospital on 2026-02-04.