Recruiting

Hand Grip Strength

Sponsor:

British Columbia Cancer Agency

Code:

NCT07255001

Conditions

Pancreatic Ductal Adenocarcinoma (PDAC)

Hand Grip Strength

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Hand grip strength assessments using a dynamometer

Study Details

Brief summary:

The goal of this clinical trial is to measure hand grip strength in adults with pancreatic ductal adenocarcinoma (PDAC). The main questions it aims to answer are:

  • Is it feasible to measure hand grip strength as part of a clinic visit?
  • Are changes in hand grip strength related to changes in body composition?
  • Is hand grip strength related to a person's well-being?
  • Is hand grip strength related to how a tumour responds to treatment?

Participants will squeeze a device with their hand to measure their hand grip strength and complete questionnaires about their well-being when they are seen in clinic for their regular medical care for PDAC.

Conditions

Pancreatic Ductal Adenocarcinoma (PDAC)

Hand Grip Strength

Study ID

NCT07255001

Start date

Aug 13, 2026

Status verified date

Sep, 2026

Completion date

Dec 31, 2027

Anticipated

Primary completion date

Dec 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age 18 years or older.
  • Histological and/or radiological diagnosis of resectable, non-resectable, or metastatic PDAC. For resectable PDAC, adjuvant setting only.
  • ECOG performance status 0-2.
  • Life expectancy greater than 6 months as judged by the investigator.
  • Planned for treatment, either as part of routine care or in combination with an investigational agent within another study.
  • Ability to hold a dynamometer with one hand.

Exclusion Criteria:

  • Individuals with CT imaging performed outside of Vancouver, BC, Canada.
  • Individuals who are unfit to undergo CT imaging of the third lumbar vertebra (L3).
  • Individuals who are currently participating in a structured moderate intensity resistance training program.
  • Individuals who are otherwise judged by the investigator to be unfit to proceed with this protocol.
  • Unable to comply with study assessments and follow-up.

Study Design

Enrollment

50 participants

Anticipated

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Main Study Arm

The study arm all participants are enrolled into. Participants will complete hand grip strength assessments and questionnaires.

Interventions

Hand grip strength assessments using a dynamometer

Squeeze a dynamometer with one hand to measure hand grip strength.

Primary outcome measure

  • Frequency of Participants with Hand Grip Strength (HGS) Measurements at 6 Months From Treatment Start Date [ Time Frame: From the date anti-cancer therapy is initiated until the 6-month follow-up assessment. ]

Central Contacts and Locations

Central contacts

Daniel J Renouf, MD, MPH

800-663-3333drenouf@bccancer.bc.ca

Locations

BC Cancer

Recruiting

Vancouver, British Columbia, Canada, V5Z 4E6

Contacts

Daniel J Renouf, MD, MPH

800-663-3333drenouf@bccancer.bc.ca

More Information

Sponsor

British Columbia Cancer Agency

Last update posted

Sep 15, 2026

Last verified

Sep, 2026

Keywords

  • Pancreatic ductal adenocarcinoma (PDAC)
  • Hand grip strength (HGS)
  • Quality of Life (QOL)
  • Body composition
  • Cachexia
  • Sarcopenia
  • Physical function
  • Skeletal muscle
  • Adipose tissue

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-16. This information was provided to ClinicalTrials.gov by British Columbia Cancer Agency on 2026-09-15.