Recruiting

Indoor Temperature Limit

Sponsor:

University of Ottawa

Code:

NCT07261202

Conditions

Heat Stress

Physiological Stress

Cognitive Change

Eligibility Criteria

Sex: All

Age: 10 - 15

Healthy Volunteers: Accepted

Interventions

Simulated exposure to indoor overheating

Study Details

Brief summary:

Communities worldwide are experiencing increasing heat extremes that challenge the limits of human thermoregulation, particularly among vulnerable populations such as children. Compared with adults, children are more susceptible to heat related illness due to less efficient thermoregulatory systems and difficulty recognizing early signs of heat stress. In addition, prolonged heat exposure can adversely affect their mental health, contributing to cognitive decline, heightened anxiety, and irritability. As children spend substantial time in hot environments at school and at home, and as these conditions intensify with climate change, actions to safeguard their health are essential. Yet our understanding of heat exposure effects in children remains incomplete, hindering the development of evidence based strategies to protect them.

To address this gap, the investigators aim to evaluate whether an indoor temperature limit of 26 °C (45 percent relative humidity), the upper threshold recommended to protect older adults, can effectively prevent dangerous increases in physiological strain and declines in cognitive function in children during a simulated daylong heatwave. The preliminary study will assess physiological and cognitive responses in children aged 10 to 15 years during a 6 hour exposure (approximating a typical school day) to two conditions: (1) the recommended indoor temperature upper limit (26 °C) and (2) a high heat condition representative of homes and schools without air conditioning during extreme heat events (36 °C). In both conditions, children will remain seated at rest while wearing light clothing (t shirt and shorts), with the exception of performing 15 minutes of stepping exercise (6-6.5 METS) each hour (excluding the lunch period) to reflect typical daily activity in a school setting. This experimental design will allow investigators to determine whether maintaining indoor temperatures at the recommended upper limit for older adults sufficiently mitigates physiological strain in children.

Conditions

Heat Stress

Physiological Stress

Cognitive Change

Study ID

NCT07261202

Start date

Nov 8, 2025

Status verified date

Apr, 2026

Completion date

Dec 31, 2026

Anticipated

Primary completion date

Jun 1, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 10 - 15

Healthy Volunteers: Accepted

Inclusion Criteria:

  • English or French speaking.
  • Ability to provide informed assent.

Exclusion Criteria:

  • Chronic health conditions
  • Endurance exercise training (greater than 3 sessions of vigorous exercise training per week for 30 minutes or more)
  • Restrictions to physical activity

Study Design

Enrollment

10 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Exposure to indoor temperature upper limit of 26°C

Participants exposed daylong (6 hours) to an indoor temperature maintained at 26°C and 45% relative humidity (humidex equivalent of 29).

experimental: Exposure to hot indoor environment of 36°C

Participants exposed daylong (6 hours) to an indoor temperature maintained at 36°C and 45% relative humidity (humidex equivalent of 45).

Interventions

Simulated exposure to indoor overheating

Children exposed to a 6-hour simulated heat exposure

Primary outcome measure

  • Core temperature (Peak) during daylong exposure to indoor overheating [ Time Frame: End of 6 hour daylong exposure ]

Central Contacts and Locations

Central contacts

Locations

University of Ottawa

Recruiting

Ottawa, Ontario, Canada, K1N 6N5

Contacts

More Information

Sponsor

University of Ottawa

Last update posted

Apr 23, 2026

Last verified

Apr, 2026

Keywords

  • Indoor overheating
  • Indoor temperatures
  • Heat wave
  • Thermoregulation
  • Adolescent
  • Heat strain
  • Heat vulnerability
  • Hyperthermia
  • Youth
  • Thermal comfort
  • Physical activity

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Ottawa on 2026-04-23.