Recruiting

Resistance Exercise Training

Sponsor:

Brock University

Code:

NCT07267429

Conditions

Healthy Participants

Eligibility Criteria

Sex: All

Age: 7 - 12

Healthy Volunteers: Accepted

Interventions

Resistance training

Study Details

Brief summary:

Resistance exercise training (RET) in children and adolescents has become a popular activity, with a growing body of evidence supporting its use. Numerous studies indicate that it is safe and effective at increasing muscular strength, improving sport performance, and mitigating injury risk. Despite this evidence, there are still many unknowns with RET in children, including its mechanisms of action in enhancing muscle strength.

Neural and muscular mechanisms can improve muscle strength following RET. Neural factors include improved recruitment and firing of an individual's muscle cells, and muscular factors primarily include an increase in the size of the muscle (hypertrophy). In children, little is known about how these mechanisms relate to muscle strength.

Therefore, the purpose of this study is to non-invasively assess the mechanisms of RET-induced strength increases in children performing 12 weeks of RET, compared with a non-training control group. Broadly, muscular adaptations will be assessed using ultrasound measures, while neural mechanisms will be assessed using surface electromyography decomposition.

Conditions

Healthy Participants

Study ID

NCT07267429

Start date

Dec 1, 2025

Status verified date

Dec, 2025

Completion date

Feb, 2026

Anticipated

Primary completion date

Feb, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 7 - 12

Healthy Volunteers: Accepted

Inclusion Criteria:

  • healthy
  • able to exercise

Exclusion Criteria:

  • have consumed any medications in the past year which may affect muscle function,
  • have any prior injuries or medical diagnoses associated with altered muscular function,
  • have had an injury in the past 6 months that would limit the movements required for the training and assessment protocols,
  • have performed resistance training in the past 6 months or currently participate in competitive sports (i.e., outside of school) more than 2x/week.

Study Design

Enrollment

40 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

active comparator: Training

resistance training, 12 weeks, 2 times per week

no intervention: Control

continue with habitual physical activity

Interventions

Resistance training

progressive resistance training, 12 weeks, 2 times per week

Primary outcome measure

  • muscle strength [ Time Frame: From enrollment to the end of training at 12 weeks ]
  • Peak torque [ Time Frame: From enrollment to end of training at 12 weeks ]

Central Contacts and Locations

Central contacts

Locations

Brock University

Recruiting

Saint Catharines, Ontario, Canada, L2S3A1

Contacts

More Information

Sponsor

Brock University

Last update posted

Dec 15, 2025

Last verified

Dec, 2025

Keywords

  • Strength training
  • Resistance training

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Brock University on 2025-12-15.