Recruiting

Nouri Probiotic

Sponsor:

Daily Nouri

Code:

NCT07268404

Conditions

Metabolic Health

Eligibility Criteria

Sex: Female

Age: 18 - 45

Healthy Volunteers: Accepted

Interventions

Probiotic Blend Capsule

Placebo

Study Details

Brief summary:

The goal of this clinical trial is to learn if Daily Nouri Hormone Balance Probiotic blend can improve metabolic, inflammatory, and symptom outcomes in women.

Participants will:

  • Take the probiotic blend or placebo every day for 12 weeks
  • Complete virtual assessments and report symptoms throughout the study

Conditions

Metabolic Health

Study ID

NCT07268404

Start date

Dec 10, 2025

Status verified date

Nov, 2025

Completion date

Dec, 2026

Anticipated

Primary completion date

Oct, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18 - 45

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Self-reported irregular menstrual cycles, defined as one or more of the following:

  • Cycle length typically >35 days OR <21 days
  • Fewer than 9 menstrual periods in the past year
  • Unpredictable cycle timing (varies by >7 days month-to-month)
  • Irregular cycles present for ≥6 months
  • One or more of the following hormonal balance concerns: skin, unwanted hair growth, hair thinning, weight concerns)
  • Self-reported emotional symptoms that fluctuate with menstrual cycle, including:

  • Mood swings or irritability
  • Feelings of stress or tension
  • Low mood or feeling down
  • Difficulty with emotional regulation
  • Not currently using hormonal therapies, metformin, GLP-1 receptor agonists, or anti-androgens.
  • If taking supplements for menstrual/hormonal support: willing to discontinue for 2-week washout before baseline
  • Weight stable (+ 5 pounds) for the past 2 months, not planning to start a new diet, exercise program, or medications during study
  • Able to provide electronic informed consent.
  • Willing to complete online surveys and at-home DBS sample collection.
  • Negative home pregnancy test at baseline.
  • Access to a computer or smartphone and reliable internet connection.

Study Design

Enrollment

60 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Intervention: Dietary Supplement Capsule

Hormone Balance Probiotic blend

placebo comparator: Placebo: Capsule

Identical capsule containing inactive ingredients

Interventions

Probiotic Blend Capsule

Hormone Balance Probiotic Blend

Placebo

Placebo

Primary outcome measure

  • Women's Health Quality of Life Scores [ Time Frame: From baseline to week 12 ]

Central Contacts and Locations

Locations

Alethios, Inc.

Recruiting

San Francisco, California, United States, 94109

Contacts

Alethios

(650) 206-8006support@alethios.com

More Information

Sponsor

Daily Nouri

Last update posted

Aug 25, 2026

Last verified

Nov, 2025

Keywords

  • dietary supplement
  • quality of life
  • women's health
  • hormone balance

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Daily Nouri on 2026-08-25.