Recruiting

Dry Needling

Sponsor:

Beth Israel Deaconess Medical Center

Code:

NCT07270276

Conditions

Trigger Point in Trapezius Muscle

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Dry Needling

Sham Treatment

Study Details

Brief summary:

The goal of this interventional study is to determine how well dry-needling can treat pain in people with Myofascial Pain Syndrome. The main questions it aims to answer are:

  • Does dry needling improve pain for people with a trigger point (a tender, tight spot in the muscle)?
  • How well can Electrical Impedence Myography (EIM), Myofiber Threshold Tracking (TT), and Ultrasound (US) detect changes in the muscle related to dry needling treatment?

Researchers will compare dry needling to a placebo (a treatment that does not enter the trigger point) to see if dry needling works to treat Myofascial Pain Syndrome with trigger points in the trapezius muscle (the muscle that extends over the back of the neck and shoulders), as measured by these three outcome measures (EIM, US, TT).

Participants will:

  • Visit the clinic twice: once to receive dry needling treatment, and once for a follow-up
  • Have muscle measurements taken before treatment and at follow-up
  • Have a daily survey to record the intensity of their pain

Conditions

Trigger Point in Trapezius Muscle

Study ID

NCT07270276

Start date

Feb 1, 2026

Status verified date

Feb, 2026

Completion date

Aug 31, 2028

Anticipated

Primary completion date

Mar 1, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Ages 18-80
  • Presence of active trigger points with involvement of upper trapezius
  • Able to manage breakthrough pain with acetaminophen only, excluding stable doses of pain medications at time of enrollment, which can be continued

Exclusion Criteria:

  • Multiple active trigger points in the trapezius muscle if physician assessment concludes that this may interfere with subject's ability to detect changes in pain improvement from trigger point therapy
  • Presence of cervical radicular pain, superimposed neuromuscular disease or condition that, in the opinion of the investigator, could confound interpretation of the data acquired from trapezius.
  • Fibromyalgia or other generalized pain condition
  • Opioid usage in the past 3 months
  • Active substance use disorder
  • Not on a stable dose for at least two weeks prior to study enrollment or unwilling to maintain a stable dose for duration of the study of the following drugs:

1. SSRIs, such as citalopram, escitalopram, fluoxetine, sertraline,
2. SNRIs, such as duloxetine, milnacipran, and venlafaxine
3. Tricyclic antidepressants, such as notritptyline, amitriptyline, and desipramine
4. Alpha 2 delta ligands: pregabalin, gabapentin
5. Specific anti-epileptics: topiramate, lamotrigine, oxcarbazepine, and phenytoin
6. Other: quinidine, mexiletine, and dalfampridine
  • Skin allergy or sensitivity that would preclude the use of adhesive electrodes
  • Significant systemic or psychiatric illness that in the opinion of the site Investigator would interfere with the individual's ability to participate in the trial
  • Anticoagulation (with coumadin, clopidogrel, or direct oral anticoagulants; aspirin acceptable)
  • TrP needle-based therapy in the past six weeks of the TrP to be studied
  • Body mass index > 35 kg/m2
  • Other factor that in the opinion of the site investigator would interfere with the ability to perform the study procedures

Study Design

Enrollment

70 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Dry Needling Treatment Group

placebo comparator: Sham/Placebo Treatment Group

Interventions

Dry Needling

A physical therapy and pain management technique where a small is inserted into a trigger point (tight, tender spots in the muscle that cause pain) and maneuvered to provide pain relief.

Sham Treatment

Treatment where a sham treatment will be administered which does not directly target the trigger point. Subjects will not be able to tell the difference between dry needling and sham treatment.

Primary outcome measure

  • Excitability threshold tracking (TT) [ Time Frame: From enrollment to end of treatment follow up (2 weeks) ]

Central Contacts and Locations

Locations

Beth Israel Deaconess Medical Center

Recruiting

Boston, Massachusetts, United States, 02215

Contacts

Tatyana Okanlomo Clinical Research Coordinator

617-667-3083tokanlom@bidmc.harvard.edu

More Information

Sponsor

Beth Israel Deaconess Medical Center

Last update posted

Feb 24, 2026

Last verified

Feb, 2026

Keywords

  • Myofascial Pain
  • Trigger Point
  • Myofascial Pain Syndrome
  • Trapezius Muscle Pain

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Beth Israel Deaconess Medical Center on 2026-02-24.