Recruiting

Group Exercise

Sponsor:

Colorado State University

Code:

NCT07290309

Conditions

Cancer

Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)

Physical Activity

Physical Activity Behavior

Cancer (With or Without Metastasis)

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Virtually Supervised Exercise Sessions

Asynchronous Group

Study Details

Brief summary:

The goal of this research study is to look at how live, online group exercise compares to recorded videos for helping increase physical activity levels, improve physical fitness and quality of life, and reduce loneliness among those living with and beyond cancer. The following aims have been established for this study:

  • Aim 1: Examine the effect of a group-based videoconference physical activity (PA) intervention on moderate to vigorous physical activity \[MVPA\] (i.e., aerobic and resistance exercise).
  • Aim 2: Examine the effect of the intervention on additional health-related outcomes including physical fitness (i.e., aerobic endurance, muscular strength), and quality of life at both timepoints.
  • Aim 3: Explore potential mediators and moderators of intervention effects. We will examine mediators (e.g., self-efficacy, outcome expectations, group cohesion) and moderators (e.g., age, cancer stage, neighborhood walkability) of the intervention on MVPA.
  • Exploratory Aim: Determine whether a group-based videoconference PA intervention reduces loneliness among cancer survivors.

Researchers will randomize participants into one of two guided exercise groups that are 12-weeks long in duration. Participants will be asked to complete online fitness assessments and surveys as well as wear a physical activity monitor device and watch a few times throughout the study. The whole study is 9-months long in duration with a 6-month free-living period where no study activities will take place.

Conditions

Cancer

Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)

Physical Activity

Physical Activity Behavior

Cancer (With or Without Metastasis)

Study ID

NCT07290309

Start date

Feb 6, 2026

Status verified date

Mar, 2026

Completion date

Mar 1, 2030

Anticipated

Primary completion date

Dec 1, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Able to speak/read English,
  • Diagnosed with any type of cancer within the last 5 years
  • Completed primary or adjuvant treatment (i.e., chemotherapy, radiation therapy, surgery) with no planned treatment within the next nine months. This does not include long-term or chronic therapies such as anti-hormone or targeted therapies (e.g., aromatase inhibitor, androgen deprivation therapy, immunotherapies)

Exclusion Criteria:

  • Existing participation in ≥150 minutes per week of at least moderate intensity aerobic exercise
  • Known contraindications for non-medically supervised moderate or greater intensity exercise (e.g., uncontrolled hypertension, inability to walk without an assistive device)
  • Current or planned participation in another structured program or intervention intended to encourage participation in exercise or physical activity.

Study Design

Enrollment

300 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Intervention (Virtually Supervised Exercise Class)

Live, group-based exercise classes will be delivered 2x per week on Zoom for 12-weeks along with a total of 5 behavior change discussion sessions.

active comparator: Comparator (Asynchronous Exercise Sessions)

Participants will watch pre-recorded exercise and discussion videos for 12-weeks.

Interventions

Virtually Supervised Exercise Sessions

The 12-week intervention will consist of supervised exercise sessions twice per week, and PA behavior change discussion sessions twice per month (bi-weekly) throughout the study for a total of five sessions (Week 2, 4, 6, 8 and 10). Exercise and PA behavior change discussion sessions will be informed by social cognitive theory, operationalize several BCT's, and include group dynamics-based strategies to enhance group cohesion. Exercise sessions will take place twice per week, lasting approximately one hour.

Asynchronous Group

The comparator will be an "unsupported intervention",128 which will use the same technology and provide the same content as the intervention but subtract the human components. Participants in the control group will receive access to pre-recorded (i.e., asynchronous) videos of the exercise and discussion sessions. The exercise videos will follow the same format as those in the intervention (i.e., instructor led, circuit-style aerobic and resistance exercises). Discussion sessions will operationalize the same BCT's using PowerPoint slides. Comparator arm participants will receive instructions on how to access these videos via a unique participant login to a secure website, Canvas, the same recommendations to achieve PA guidelines, and the same home-based exercise equipment (along with instructions for use).

Primary outcome measure

  • Change in accelerometer measured moderate to vigorous physical activity from baseline to 3- and 6-month follow-up [ Time Frame: Assessed at baseline, 3-and 6-month follow-up ]
  • Change in self-reported moderate-to-vigorous intensity physical activity from baseline to 3 and 6 month follow-up [ Time Frame: Assessed at baseline, 3 and 6-month follow-up ]

Central Contacts and Locations

Central contacts

Heather J Leach, PhD

(970) 491-8951heather.leach@colostate.edu

Elena M Lancioni, MPH

elena.lancioni@colostate.edu

Locations

Human Performance Clinical Research Lab

Recruiting

Fort Collins, Colorado, United States, 80523

Contacts

Elena Lancioni

970-491-4653patplab@colostate.edu

More Information

Sponsor

Colorado State University

Last update posted

Mar 31, 2026

Last verified

Mar, 2026

Keywords

  • Exercise oncology
  • Physical activity for cancer survivors
  • Group based exercise
  • Virtual exercise
  • physical activity
  • exercise
  • remote study
  • Cancer survivors

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Colorado State University on 2026-03-31.