Recruiting

Reishi Mushroom

Sponsor:

Efforia, Inc

Code:

NCT07294482

Conditions

Sleep

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Bristol Fungarium's 1:4 Reishi Mushroom Tincture

Study Details

Brief summary:

Examining the effects of 1ml of Reishi mushroom extract (1:4 extraction ratio, two hot water extractions and an alcohol extraction), taken daily, 30 mins before bed on perceived sleep quality and stress levels. Sleep quality includes: duration, sleep onset latency, nighttime wakings, and perceived restfulness. And consequently, the potential for increased daytime energy levels and a reduction in perceived stress levels.

Conditions

Sleep

Study ID

NCT07294482

Start date

Sep 10, 2025

Status verified date

Dec, 2025

Completion date

Sep 10, 2026

Anticipated

Primary completion date

Sep 10, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Can read and understand English.
  • US resident.
  • Willing and able to follow the requirements of the protocol.

Exclusion Criteria:

  • Individuals with Allergies
  • Pregnant or Nursing Women
  • Individuals on Anticoagulants
  • Immunocompromised Individuals
  • Individuals with Liver Disease
  • Children and Adolescents
  • Individuals with Chronic Illnesses
  • Those with Mental Health Disorders

Study Design

Enrollment

100 participants

Anticipated

Intervention Model

Single group

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

experimental: Single arm where participants act as their own control

Single Arm observational where participants act as their own control

Interventions

Bristol Fungarium's 1:4 Reishi Mushroom Tincture

UK-grown organic Reishi tincture, cloned in lab. Triple Extracted, 1: 4 Ratio via two hot water extractions and a final organic ethanol extraction to gain access to all the bioactive compounds responsible for Reishi's beneficial properties. (1g of mushrooms to every 4ml of water).

Primary outcome measure

  • Perceived Stress Scale (Past Week Version) [ Time Frame: Change from baseline (Day 1-5) in perceived stress levels at 4-5 weeks after the start of the intervention ]
  • Neuro-QOL Item Bank v1.0 -Fatigue - Short Form [ Time Frame: Change from baseline (Day 1-5) in fatigue levels at 6-7 weeks after the start of the intervention ]
  • PROMIS Sleep Disturbance Scale [ Time Frame: Change from baseline (Day 1-5) in sleep disturbance levels at 6-7 weeks after the start of the intervention ]

Central Contacts and Locations

Central contacts

Matthew Amsden

646-679-2479help@efforia.com

Locations

Efforia

Recruiting

New York, New York, United States, 10003

Contacts

Matthew Amsden

(646) 679-2479help@efforia.com

More Information

Sponsor

Efforia, Inc

Last update posted

Dec 26, 2025

Last verified

Dec, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Efforia, Inc on 2025-12-26.