Recruiting

Body Composition Measurements

Sponsor:

Pennington Biomedical Research Center

Code:

NCT07305753

Conditions

Healthy Participants

Young Healthy Adults

Elderly (People Aged 65 or More)

Eligibility Criteria

Sex: All

Age: 20 - 70+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The aim of this study is to develop a dataset with reference body composition measurements using criterion methods. This dataset will be used to develop new protocols to study patients with cancer. Obtaining measurements of sodium bromide (NaBr), deuterium dilution (D2O), and D3-Creatine in a stratified sample of adults will determine the accuracy (and precision) of the available devices for ECW, TBW, and skeletal muscle mass measurements.

Conditions

Healthy Participants

Young Healthy Adults

Elderly (People Aged 65 or More)

Study ID

NCT07305753

Start date

Oct 15, 2025

Status verified date

Dec, 2025

Completion date

May 30, 2026

Anticipated

Primary completion date

Apr 15, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 20 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Being either male or female
  • Being an adult >20 - <40 or >70 years of age.
  • Having a body weight of less than 440 pounds
  • Being willing to comply with the study procedures
  • Not having a chronic illness (e.g., diabetes, cancer, etc.)
  • Must be willing to have biospecimens and imaging stored for research use

Exclusion Criteria:

  • Being pregnant, attempting to become pregnant, or breastfeeding
  • Having medical implants such as a pacemaker or metal joint replacements
  • Having had a mastectomy, breast reduction, or breast implants
  • Having hair that cannot fit in a swim cap
  • Having a body weight greater than 440 pounds
  • Taking medications that alter the body's fluid compartments (ex: diuretics)
  • Not willing to have biospecimens and imaging stored for future research use.

Study Design

Enrollment

40 participants

Anticipated

Interventions and Outcome Measures

Arms

Cross-sectional group

20 young (20-40yo) and 20 older (70+) adults

Primary outcome measure

  • Skeletal Muscle Mass [ Time Frame: Single time point ]

Central Contacts and Locations

Central contacts

Steven B Heymsfield, MD

2257632541steven.heymsfield@pbrc.edu

Locations

Pennington Biomedical Research Center

Recruiting

Baton Rouge, Louisiana, United States, 70808

Contacts

Steven B Heymsfield, MD

2257632541steven.heymsfield@pbrc.edu

More Information

Sponsor

Pennington Biomedical Research Center

Last update posted

Dec 26, 2025

Last verified

Dec, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Pennington Biomedical Research Center on 2025-12-26.