Recruiting

Intercostal Neuralgia

Sponsor:

Sunnybrook Health Sciences Centre

Code:

NCT07308587

Conditions

Intercostal Nerve Injury

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Chest tube insertion

Study Details

Brief summary:

Traumatic rib fractures are common injuries following blunt chest trauma, often requiring chest tube insertion to manage complications such as pneumothorax or haemothorax. However, chest tube placement can lead to intercostal nerve injury, resulting in intercostal neuralgia-a debilitating condition characterized by chronic, neuropathic pain along the intercostal nerves. Despite its clinical significance, the incidence, risk factors, and long-term outcomes of intercostal neuralgia in this patient population remain poorly understood.

Chronic pain following thoracic trauma, including intercostal neuralgia, has been shown to significantly impair quality of life and functional outcomes, leading to prolonged disability and increased healthcare utilization. Current literature highlights the need for better understanding and management of this condition, particularly in patients undergoing invasive procedures such as chest tube insertion. This study aims to prospectively evaluate the development of intercostal neuralgia in patients with chest tube insertion following traumatic rib fractures.

Conditions

Intercostal Nerve Injury

Study ID

NCT07308587

Start date

Jan 19, 2026

Status verified date

Apr, 2026

Completion date

Dec 31, 2027

Anticipated

Primary completion date

Dec 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adults (≥18 years) with traumatic rib fractures requiring chest tube insertion
  • Chest tube or pigtail insertion performed during their initial hospitalization for trauma

Exclusion Criteria:

  • Patients with spinal cord injury
  • Inability to complete follow-up assessments (e.g., language barriers, lack of telephone access)

Exclusion Criteria:

  • Patients with traumatic brain injury
  • Patients with spinal cord injury
  • Inability to complete follow-up assessments (e.g., language barriers, lack of telephone access)

Study Design

Enrollment

100 participants

Anticipated

Interventions and Outcome Measures

Arms

Chest tube inserted

Patients with acute traumatic rib fracture/chest injury requiring chest tube insertion

Interventions

Chest tube insertion

Insertion of chest tube

Primary outcome measure

  • Incidence of intercostal neuralgia [ Time Frame: 1 and 3 months ]

Central Contacts and Locations

Locations

Sunnybrook Health Sciences Centre

Recruiting

Toronto, Ontario, Canada, M4N 3M5

Contacts

More Information

Sponsor

Sunnybrook Health Sciences Centre

Last update posted

May 15, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Sunnybrook Health Sciences Centre on 2026-05-15.