Recruiting

Observational Study

Sponsor:

Mayo Clinic

Code:

NCT07311044

Conditions

Pulmonary Hypertension

Cardiovascular Diseases

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The purpose of this study is to determine the association between patient voice signal characteristics and the presence and severity of pulmonary hypertension in patients referred for elective clinically indicated echocardiography for at Mayo Clinic MN.

Conditions

Pulmonary Hypertension

Cardiovascular Diseases

Study ID

NCT07311044

Start date

Jan 8, 2021

Status verified date

Dec, 2025

Completion date

Jan, 2027

Anticipated

Primary completion date

Jan, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • All individuals who present for a routine elective, clinically indicated, diagnostic echocardiogram at the echocardiography laboratory at Mayo Clinic
  • All individuals who have had a clinically indicated, diagnostic echocardiogram at the echocardiography lab at Mayo Clinic before a scheduled procedure in the cardiac catheterization lab at Mayo Clinic
  • All individuals who have had a clinically indicated diagnostic echocardiogram at the echocardiography lab at Mayo Clinic and have an appointment in any CV outpatient clinic.

Exclusion Criteria:

  • Known history of voice disorder either primary or secondary to neuromuscular or other pathology
  • Patients under the age of 18 years

Study Design

Enrollment

7000 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Number of confirmed pulmonary hypertension diagnoses based on voice recording analysis [ Time Frame: Baseline ]

Central Contacts and Locations

Central contacts

Diana Albers

507-255-6884albers.diana2@mayo.edu

Amir Lerman, M.D.

lerman.amir@mayo.edu

Locations

Mayo Clinic

Recruiting

Rochester, Minnesota, United States, 55905

Contacts

Diana Albers

507-255-6884albers.diana2@mayo.edu

Principal Investigator:

Amir Lerman, MD

More Information

Sponsor

Mayo Clinic

Last update posted

Dec 30, 2025

Last verified

Dec, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2025-12-30.