Recruiting

Get Real and Heel

Sponsor:

UNC Lineberger Comprehensive Cancer Center

Code:

NCT07313306

Conditions

Breast Cancer

Metastatic Breast Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

The Real and Heel (GRH)

Study Details

Brief summary:

This study will examine unmet exercise needs among patients with metastatic breast cancer (MBC) at UNC and assess whether participation in Get Real and Heel (GRH) can increase physical activity. The proposed research aims to improve multiple domains of well-being, quality of life, physical function, social support and reduce social isolation through a community based exercise intervention. By leveraging underutilized University of North Carolina Chapel Hill (UNC) resources, this work seeks to reduce barriers to accessibility, awareness, and appropriateness of exercise programming for this underserved population. Findings will help close the gap between patients' exercise needs, interest, and participation, with potential benefits for symptoms, functioning, and quality of life.

Conditions

Breast Cancer

Metastatic Breast Cancer

Study ID

NCT07313306

Start date

Dec 15, 2025

Status verified date

Jan, 2026

Completion date

Jul 1, 2028

Anticipated

Primary completion date

Jul 1, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

In order to participate in this study a subject must meet all of the eligibility criteria outlined below.

Inclusion Criteria:

  • Written informed consent obtained to participate in the study and HIPAA authorization for release of personal health information.
  • Subjects are willing and able to comply with study procedures based on the judgement of the investigator or protocol designee.
  • Age > 18 years at the time of consent.
  • Diagnosis of metastatic breast cancer within two years of consent date
  • Receives medical clearance from clinical team for moderate intensity exercise programming
  • Indicates intent to receive ongoing cancer care at the enrolling institution
  • English Speaking - program and measures are in English and not practicably translatable for a study this size.

Exclusion Criteria:

  • Currently on hospice.
  • Bed-bound status or other contraindication to exercise
  • Participation in GRH since their diagnosis with MBC

Study Design

Enrollment

50 participants

Anticipated

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Metastatic breast cancer (MBC) receive Get Real and Heel (GRH)

Participants will receive Get Real and Heel (GRH) exercise program.

Interventions

The Real and Heel (GRH)

The Get Real and Heel (GRH) program is a 16-week exercise intervention developed at the University of North Carolina at Chapel Hill (UNC).

Primary outcome measure

  • Feasibility of referral to Get Real and Heel [ Time Frame: Up to 16 weeks ]

Central Contacts and Locations

Central contacts

Kristen Jarman

919-984-0000jkristen@email.unc.edu

Locations

Lineberger Comphrehensive Cancer Center at University of North Carolina at Chapel Hill

Recruiting

Chapel Hill, North Carolina, United States, 27599

Principal Investigator:

Sasha E Knowlton, MD

More Information

Sponsor

UNC Lineberger Comprehensive Cancer Center

Last update posted

Jan 20, 2026

Last verified

Jan, 2026

Keywords

  • Get Real and Heel (GRH)
  • physical activity
  • exercise
  • quality of life
  • social support

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by UNC Lineberger Comprehensive Cancer Center on 2026-01-20.