Recruiting

Observational Study

Sponsor:

Mayo Clinic

Code:

NCT07325006

Conditions

Hematopoietic and Lymphatic System Neoplasm

Malignant Solid Neoplasm

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Non-Interventional Study

Study Details

Brief summary:

This evaluates the impact of physician behaviors and other factors experienced during radiation treatment influence distress levels in cancer patients.

Conditions

Hematopoietic and Lymphatic System Neoplasm

Malignant Solid Neoplasm

Study ID

NCT07325006

Start date

Nov 24, 2025

Status verified date

Jul, 2026

Completion date

Nov 30, 2030

Anticipated

Primary completion date

Nov 30, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adult (age 18+ years old)
  • Must have a diagnosis of neoplasm
  • Must be actively undergoing radiation therapy (RT) or have completed RT within the last month at Mayo Clinic in Rochester
  • Able to read and write in English
  • Must have email and Mayo Clinic patient portal access

Exclusion Criteria:

  • Patients who have not yet started RT
  • Patients who have been seen in consultation but not recommended for radiation

Study Design

Enrollment

5000 participants

Anticipated

Interventions and Outcome Measures

Arms

Observational

Patients complete a survey and have their medical records reviewed on study. Patients who score a 7 or higher on the NCCN distress thermometer receive distress management patient education materials and recommendation to follow up with their care team.

Interventions

Non-Interventional Study

Non-interventional study

Primary outcome measure

  • Explore what physician behaviors contribute to patients' cancer distress [ Time Frame: Baseline (at enrollment) ]
  • Explore what physician behaviors lessen patients' cancer distress [ Time Frame: Baseline (at enrollment) ]
  • Explore how non-physician factors in the patient care experience contribute to patients' cancer distress [ Time Frame: Baseline (at enrollment) ]
  • Explore how non-physician factors in the patient care experience lessen patients' cancer distress [ Time Frame: Baseline (at enrollment) ]
  • Patient ratings of preference for physician-initiated conversations [ Time Frame: Baseline (at enrollment) ]
  • Patient ratings of contributors to distress [ Time Frame: Baseline (at enrollment) ]

Central Contacts and Locations

Central contacts

Clinical Trials Referral Office

855-776-0015mayocliniccancerstudies@mayo.edu

Locations

Mayo Clinic in Rochester

Recruiting

Rochester, Minnesota, United States, 55905

Contacts

Clinical Trials Referral Office

855-776-0015mayocliniccancerstudies@mayo.edu

Principal Investigator:

May Elbanna, MB, BCh, PhD

More Information

Sponsor

Mayo Clinic

Last update posted

Jul 7, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-07-07.