Recruiting

Metacognitive Strategy Training

Sponsor:

University of Pittsburgh

Code:

NCT07331896

Conditions

Stroke

Neglect, Hemispatial

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Strategy Training

Attention Control

Study Details

Brief summary:

It is common for individuals after stroke to have a cognitive perceptual impairment called unilateral spatial neglect (neglect). Individuals with neglect have difficulty paying attention to one side of their body or one side of the environment and therefore experience difficulty performing daily activities. There are a lack of effective treatments for neglect and new interventions are needed to help reduce disability for these individuals. Metacognitive strategy training (strategy training) is an intervention that has the potential to reduce neglect-related disability and improve individuals' attention and awareness of their neglect. This study seeks to examine the effects of strategy training on neglect, self-awareness, and disability, specifically for individuals who are living in the community after their stroke.

Conditions

Stroke

Neglect, Hemispatial

Study ID

NCT07331896

Start date

Apr 6, 2026

Status verified date

May, 2026

Completion date

Jan, 2029

Anticipated

Primary completion date

Jan, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • had a stroke
  • presence of neglect as determined by score of <18 or 2 or more collisions on the Virtual Reality Lateralized Attention Test (VRLAT); score below established cutoff for neglect on one of the six subtests of the Behavioral Inattention Test (BIT); OR reported signs/symptoms of neglect
  • ≥18 years old
  • lives within 30 miles of the University of Pittsburgh in a community dwelling.

Exclusion Criteria:

  • Boston Diagnostic Aphasia Examination (BDAE) Severity Scale score of 0
  • dementia per medical record
  • active major depressive disorder per medical record
  • not willing to be videotaped
  • subject is currently receiving rehabilitation therapy as part of their usual care

Study Design

Enrollment

45 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Strategy Training

The strategy training intervention teaches individuals to develop personalized goals, self-assess their performance of daily activities, and develop and evaluate strategies designed to overcome barriers and improve their performance of daily activities. Participants use a workbook to support their application of the strategy training.

active comparator: Attention Control

The attention control intervention controls for the non-specific effects of strategy training. The study team will administer the standardized and dose-matched protocol, using scripted open-ended questions to facilitate participants' reflections on their rehabilitation activities and experiences. Participants complete a daily journal, merely reviewing their rehabilitation activities.

Interventions

Strategy Training

This intervention will use an adapted form of strategy training for people with neglect.

Attention Control

This intervention will use a reflective listening protocol.

Primary outcome measure

  • Change in attention/neglect [ Time Frame: Baseline to Post-intervention (up to 60 days) ]

Central Contacts and Locations

Central contacts

Emily Grattan, PhD, OTRlL

412-648-0619esg39@pitt.edu

Locations

University of Pittsburgh

Recruiting

Pittsburgh, Pennsylvania, United States, 15260

More Information

Sponsor

University of Pittsburgh

Last update posted

May 12, 2026

Last verified

May, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Pittsburgh on 2026-05-12.