Recruiting

Observational Study

Sponsor:

HALEON

Code:

NCT07337109

Conditions

Dentin Hypersensitivity

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The primary purpose of this study is to characterize changes in Oral-Health-Related Quality of Life (OHrQoL), as measured by the Dentin Hypersensitivity Experience Questionnaire (DHEQ) over a 12-month period.

Conditions

Dentin Hypersensitivity

Study ID

NCT07337109

Start date

Dec 16, 2025

Status verified date

Apr, 2026

Completion date

Feb, 2027

Anticipated

Primary completion date

Feb, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Participant who has provided consent indicating they have been informed of all pertinent aspects of the study.
  • All genders who, at the time of screening, are aged more than or equal to (>=)18 years.
  • Anyone who has begun to experience dentin hypersensitivity (self-reported) within the past three months.
  • Anyone who has started to use products to treat their tooth sensitivity within the past three months.
  • Participant who is able to independently complete all activities online.
  • Participants residing in the United States.

Exclusion Criteria:

  • Anyone who has any chronic health conditions that could impact their participation in this study, such as cancer, mental health disorders, history of serious illness in the last three months, history of substance abuse, or planned surgery during the study period.
  • Participant whose sensitivity could be caused by other factors or clinical pathology than DH, as self-reported on the screening questionnaire, which include:

1. Anyone who suffers from tooth cavities, significant gum disease, cracked or fractured teeth, temporomandibular joint disease (TMD), or who has had tooth extractions or fillings within the last three months.
2. Anyone who wears braces (including Invisalign-like appliances) for treatment or dentures (full or partial).
3. Participant who has undergone treatment for periodontal or gum disease within 6 months of screening or is currently undergoing treatment for periodontal or gum disease.
4. Participant who has been informed by a Dental Health Care Professional (DHCP) that they have active periodontitis.
5. Participant who has been informed by a DHCP that they have active caries.
6. Participant with any chronic and/or severe painful health condition(s) which lead to regular use of pain relief medications (more than 3 days a week).
  • Anyone who has participated in another dentin hypersensitivity study within the last three months.
  • Currently participating in another research study or will be participating in any other research study at any point during this study's duration.

Study Design

Enrollment

375 participants

Anticipated

Interventions and Outcome Measures

Arms

New sufferers of self-reported Dentin Hypersensitivity aged 18+ years

Primary outcome measure

  • Change From Baseline in Total DHEQ Score Over 12 Months [ Time Frame: Baseline and up to 12 Months ]

Central Contacts and Locations

Central contacts

Locations

Citruslabs (Virtual Site)

Recruiting

Las Vegas, Nevada, United States, 89118

More Information

Sponsor

HALEON

Last update posted

Apr 28, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by HALEON on 2026-04-28.