Recruiting

Same-Day Hemodialysis

Sponsor:

Stanford University

Code:

NCT07339202

Conditions

Perioperative Management

End Stage Kidney Disease (ESRD)

Hemodialysis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Same-Day Hemodialysis

No Same-Day Hemodialysis

Study Details

Brief summary:

The goal of this clinical trial is to evaluate the feasibility of two different preoperative hemodialysis schedules for people with end-stage kidney disease (ESKD) who undergo surgical procedures. The main questions it aims to answer are:

Is it feasible to randomize participants with ESKD undergoing nonemergent surgical procedures to same-day hemodialysis versus no same-day hemodialysis?

Is it safe to randomize participants with ESKD undergoing nonemergent surgical procedures to same-day hemodialysis versus no same-day hemodialysis?

Researchers will compare the two hemodialysis schedules to see if the scheduling and safety profiles are the same.

Participants will:

Answer questions about their health up to 4 weeks before and 4 weeks after the surgical procedure.

Receive hemodialysis on the day of the surgical procedure or not, depending on the study treatment assignment.

Conditions

Perioperative Management

End Stage Kidney Disease (ESRD)

Hemodialysis

Study ID

NCT07339202

Start date

May 27, 2026

Status verified date

Jun, 2026

Completion date

Oct 15, 2027

Anticipated

Primary completion date

Sep 15, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Patient is willing to comply with all study procedures for the duration of the study
2. Patient has a diagnosis of ESKD
3. Patient initiated hemodialysis at least 90 days prior to the planned surgical procedure
4. Patient is treated with a stable hemodialysis schedule, defined as an average of 2.5- 3.5 hemodialysis sessions per week in the preceding 4 weeks prior to surgery
5. Patient is scheduled to undergo nonemergent surgical procedures in the Stanford Health Care system. This includes (but is not limited to):

  • Fistula or graft creation, revision, or removal
  • Fistulogram
  • Peritoneal dialysis catheter placement or revision
  • Lower extremity angiogram (including femoral and iliac vessels)
  • Lower extremity bypass (including femoral and iliac vessels)
  • Lower extremity amputation
  • Lower extremity endarterectomy (including femoral and iliac vessels) Of note, this list of procedures is not exhaustive and other procedures may be considered that meet inclusion criteria and no exclusion criteria, in consultation with the treatment teams involved.

Exclusion Criteria:

1. Patient is pregnant
2. Patient is a prisoner
3. Patient is < 18 years old
4. The treating clinicians determine that the patient's clinical condition necessitate a specific approach to surgical scheduling or preoperative hemodialysis

Study Design

Enrollment

30 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Same-Day Hemodialysis

Participants will receive same-day hemodialysis, defined as a hemodialysis treatment prior to the surgical procedure but on the same calendar day as the surgical procedure (typically in the morning prior to the procedure).

active comparator: No Same-Day Hemodialysis

Participants will not receive same-day hemodialysis, defined as a hemodialysis treatment prior to the surgical procedure but on the same calendar day as the surgical procedure.

Interventions

Same-Day Hemodialysis

Hemodialysis treatment prior to the surgical procedure but on the same calendar day as the surgical procedure (typically in the morning prior to the procedure).

No Same-Day Hemodialysis

No hemodialysis treatment prior to the surgical procedure but on the same calendar day as the surgical procedure.

Primary outcome measure

  • Number of hours from completion of the most recent preoperative hemodialysis session to entry into the operating room [ Time Frame: up to 1 day ]
  • Number of participants who experience electrolyte abnormalities or volume overload requiring additional unplanned hemodialysis, rescheduling / cancellation of the surgical procedure, or an unanticipated escalation of postoperative level of care. [ Time Frame: up to 1 day ]

Central Contacts and Locations

Locations

Stanford University

Recruiting

Stanford, California, United States, 94305

Contacts

Satvik Sharma

650-736-9368satviksh@stanford.edu

More Information

Sponsor

Stanford University

Last update posted

Jun 11, 2026

Last verified

Jun, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Stanford University on 2026-06-11.