Recruiting

Observational Study

Sponsor:

University of Rochester

Code:

NCT07356310

Conditions

Breathing

Lung Function Decreased

Asthma (Diagnosis)

Obesity

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Oscillometer

Study Details

Brief summary:

This study will determine if airway resistance to airflow and pressure, measured by Oscillometry, is associated with abnormal findings on methacholine challenge testing and whether these findings are associated with body habitus,

Conditions

Breathing

Lung Function Decreased

Asthma (Diagnosis)

Obesity

Study ID

NCT07356310

Start date

Feb 17, 2026

Status verified date

Apr, 2026

Completion date

Nov 1, 2027

Anticipated

Primary completion date

Jul 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Willingness to perform breathing test
  • Must be able to speak and understand English
  • Referred for Methacholine Challenge Test

Exclusion Criteria:

  • Unable to provide consent or perform oscillometry test

Study Design

Enrollment

100 participants

Anticipated

Interventions and Outcome Measures

Arms

Subjects with dyspnea referred for methacholine challenge testing

Subjects with dyspnea being evaluated for asthma who are referred for methacholine challenge testing

Interventions

Oscillometer

The tremoFlo C-100 Airwave Oscillometry System is intended to measure respiratory system impedance using the Forced Oscillation Technique (FOT).

Primary outcome measure

  • Oscillometer [ Time Frame: Single measurement, approximately day 1 ]

Central Contacts and Locations

Central contacts

Patrick Donohue, MD

(585) 210-9301patrick_donohue@urmc.rochester.edu

Locations

University of Rochester Medical Center

Recruiting

Rochester, New York, United States, 14620

More Information

Sponsor

University of Rochester

Last update posted

Apr 13, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Rochester on 2026-04-13.