VutrisiranDemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting

Arms

Primary outcome measure

• New York Heart Association (NYHA) Class [ Time Frame: From time of ATTR-CM diagnosis up to 5 years ]
• Outpatient Diuretic Intensification [ Time Frame: From time of enrollment for up to 5 years ]
• Norfolk Quality of Life - Diabetic Neuropathy (QOL-DN) Total Score [ Time Frame: From time of enrollment (if available) or ATTR-CM diagnosis up to 5 years ]
• Kansas City Cardiomyopathy Questionnaire (KCCQ) [ Time Frame: From time of enrollment (if available) or ATTR-CM diagnosis up to 5 years ]
• Patient Global Impressions - Change (PGI-C) [ Time Frame: From time of enrollment (if available) or ATTR-CM diagnosis up to 5 years ]
• Patient Global Impressions - Severity (PGI-S); [ Time Frame: From time of enrollment (if available) or ATTR-CM diagnosis up to 5 years ]
• Treatment Satisfaction Questionnaire for Medication version 9 (TSQM-9) [ Time Frame: From time of enrollment (if available) or ATTR-CM diagnosis up to 5 years ]