Recruiting

Breathing Intervention

Sponsor:

Mayo Clinic

Code:

NCT07369752

Conditions

Depressive Disorder

Anxiety

Adolescent

Eligibility Criteria

Sex: All

Age: 12 - 17

Healthy Volunteers: Not accepted

Interventions

Breathing Intervention

Study Details

Brief summary:

The purpose of this study is to evaluate the feasibility of a structured breathing intervention in rural and non-rural adolescents diagnosed with anxiety and depression, recruited from outpatient pediatric and child/adolescent psychiatry clinics.

Conditions

Depressive Disorder

Anxiety

Adolescent

Study ID

NCT07369752

Start date

Feb 19, 2026

Status verified date

Apr, 2026

Completion date

Jan, 2027

Anticipated

Primary completion date

Jan, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 12 - 17

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adolescents between the ages of 12 and 17 who have been diagnosed with a major depressive disorder (mild or moderate) and/or an anxiety disorder.
  • Participants may have co-occurring mild to moderate alcohol or drug use problems, provided these do not require immediate specialized treatment or crisis intervention.
  • All participants must be receiving care at one of two participating MCHS outpatient psychiatry clinics and may reside in rural area (RUCA code 4-10) or non-rural area.
  • Participants must be able to read and understand English, and both parental or guardian consent and adolescent assent will be required.

Exclusion Criteria:

  • Current suicidal ideation or self-harm behavior requiring immediate clinical intervention
  • Presence of severe psychiatric comorbidities such as psychosis, bipolar disorder, depression with psychotic features, severe alcohol and drug use, or eating disorders.
  • Participants with significant cognitive impairment that would interfere with study participation.

Study Design

Enrollment

40 participants

Anticipated

Intervention Model

Single group

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: Rural adolescent patients

Rural and non-rural adolescent patients of Mayo Clinic Health Systems, aged 12 to 17 years, with a clinical diagnosis of mild to moderate anxiety and/or depression will follow a structured breathing practice (Seokmun Hoheup) at least 3 times per week.

Interventions

Breathing Intervention

Participants will follow a structured breathing practice (Seokmun Hoheup) that progresses in incremental steps, beginning with 15 minutes, increasing to 30 minutes, and then to 36 minutes per session over the course of the program.

Primary outcome measure

  • Feasibility of Intervention Measure (FIM) score [ Time Frame: 4 months ]
  • Acceptability of Intervention Measure (AIM) score [ Time Frame: 4 months ]
  • Intervention Appropriateness Measure (IAM) score [ Time Frame: 4 months ]
  • Recruitment feasibility [ Time Frame: 4 months ]
  • Retention feasibility [ Time Frame: 4 months ]

Central Contacts and Locations

Central contacts

Danielle Boos

715-464-8173boos.danielle@mayo.edu

Marin Nycklemoe

507-255-2814nycklemoe.marin@mayo.edu

Locations

Mayo Clinic Health System-Albert Lea

Recruiting

Albert Lea, Minnesota, United States, 56007

Contacts

Marin Nycklemoe

507-255-2814

Principal Investigator:

Nicholas Bormann, MD

Mayo Clinic Health System-Eau Claire Clinic

Recruiting

Eau Claire, Wisconsin, United States, 54703

Contacts

Danielle Boos

715-464-8173

Principal Investigator:

Pravesh Sharma, MD

More Information

Sponsor

Mayo Clinic

Last update posted

Apr 3, 2026

Last verified

Apr, 2026

Keywords

  • Seokmun Hoheup
  • breathing

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-04-03.