Recruiting

Educational Tool

Sponsor:

M.D. Anderson Cancer Center

Code:

NCT07382583

Conditions

Levonorgestrel

Intrauterine Systems

Prevention

Endometrial Cancer

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Survey using a questionnaire

Study Details

Brief summary:

To develop an educational tool to help patients and healthcare professionals make informed decisions about endometrial cancer and available prevention options for it (such as the use of a levonorgestrel-releasing intrauterine system \[LNG-IUS\]).

Conditions

Levonorgestrel

Intrauterine Systems

Prevention

Endometrial Cancer

Study ID

NCT07382583

Start date

Feb 12, 2026

Status verified date

Feb, 2026

Completion date

Feb 1, 2030

Anticipated

Primary completion date

Feb 1, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

This study will include participants from three categories: Unaffected women, Affected women, and Healthcare Providers. The eligibility criteria for each group are listed below:

Inclusion Criteria:

1. Unaffected women

1. Must be at least 18 years old
2. Must read and speak English or Spanish
3. Must be premenopausal
4. Must not have a prior history of EC or complex atypical hyperplasia
5. Must provide written, informed consent
6. No physical, psychological, or cognitive impairments that would preclude participation in an interview as determined by the PI or study team member
2. Affected women

1. Must be at least 18 years old
2. Must read and speak English or Spanish
3. Must have a prior history of EC or complex atypical hyperplasia
4. Must provide written, informed consent
5. No physical, psychological, or cognitive impairments that would preclude participation in an interview as determined by the PI or study team member
3. Healthcare Providers

1. Physicians or advanced practice providers (physician assistants, nurse practitioners) from Family Medicine, Obstetrics \& Gynecology, Internal Medicine, or Endocrinology
2. Must be at least 18 years old
3. Must read and speak English or Spanish
4. Must provide written, informed consent for qualitative interviews

Exclusion Criteria:

  • N/A

Study Design

Enrollment

270 participants

Anticipated

Interventions and Outcome Measures

Arms

Phase 1

Identify decisional needs, patient values and experiences

Phase 2

Develop and pilot test a web-based shared medical decision tool

Interventions

Survey using a questionnaire

Patient Preference Utility Assessment and Questionnaires

Primary outcome measure

  • Patient Utility Questionnaire [ Time Frame: Through study completion; an average of 1 year ]

Central Contacts and Locations

Central contacts

Locations

The Harris Health System (LBJ)

Recruiting

Houston, Texas, United States, 77026

Contacts

Principal Investigator:

Larissa Meyer, MD

MD Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

Contacts

Principal Investigator:

Larissa A Meyer, MD

More Information

Sponsor

M.D. Anderson Cancer Center

Last update posted

Aug 12, 2026

Last verified

Feb, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by M.D. Anderson Cancer Center on 2026-08-12.