Recruiting

Dextrose Injection

Sponsor:

Dr. Dean Reeves Clinic

Code:

NCT07382596

Conditions

PTSD

Eligibility Criteria

Sex: All

Age: 19 - 70+

Healthy Volunteers: Not accepted

Interventions

Dextrose 5% in water bilateral injection

Normal saline bilateral injection

Study Details

Brief summary:

PTSD is a chronic mental health condition that drastically reduces an individual's quality of life Dextrose injection with a small needle has been used for chronic pain patients and observational results have shown it to be effective in reducing anxiety, brain fog, and depression in patients with PTSD. This randomized trial will compare dextrose injection with an injection control of normal saline (NS)

Conditions

PTSD

Study ID

NCT07382596

Start date

May 16, 2026

Status verified date

Sep, 2026

Completion date

Apr 1, 2030

Anticipated

Primary completion date

Mar 1, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 19 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Inclusion Criteria:
  • Not involved in another study of PTSD treatment
  • Reliable transportation
  • Comfortable with computers
  • Tried 2 or more medications for treatment of PTSD symptoms
  • Tried 2 or more non-medication treatments for PTSD symptom
  • No known life-threatening illness
  • Not taking daily narcotics
  • Not having 3 or more alcoholic drinks on an average day
  • No active suicidal plans
  • No major surgery plans
  • No major life stress that might interfere with completing study
  • Symptoms for more than 1 year
  • Not planning to move for next 18 months.
  • Living within an hour of Portland, OR, Madison, WI, or Lexington, KY
  • Wiling to provide 2 email and 2 phone contact methods
  • Willing to answer questions on multiple occasions over the course of a year.
  • Willing to be assigned to 3 months of usual care treatment
  • No diagnosis of schizophrenia, Borderline Personality Disorder, or Bipolar Disorder.
  • No severe needle phobia
  • Chronic pain ≤ 5/10
  • PCL-C score ≥ 50

Exclusion Criteria:

\-

Study Design

Enrollment

50 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: D5W cervical plexus hydrodissection

10 ml D5W cervical plexus hydrodissection bilaterally at 0, 2, 4, and 8 weeks, and then by request from 13-52 weeks

active comparator: Normal saline cervical plexus hydrodissection

10 mL normal saline cervical plexus hydrodissection bilaterally at 0, 2, 4, and 8 weeks, and then D5W by request from 13-52 weeks

Interventions

Dextrose 5% in water bilateral injection

Injection under the investing fascia of the sternocleidomastoid muscle

Normal saline bilateral injection

Injection under the investing fascia of the sternocleidomastoid muscle

Primary outcome measure

  • Post traumatic checklist for civilians [ Time Frame: 3 months ]

Central Contacts and Locations

Central contacts

Kenneth D Reeves, MD

9133621600DeanReevesmd@gmail.com

Clare R Solso, RN

405 819 7777cereeves2002@hotmail.com

Locations

Wellward Medical

Recruiting

Lexington, Kentucky, United States, 40509

Contacts

Danesh Mazloomdoost, M.D.

(443) 762-3505drd@wellwardmed.com

Kenneth D Reeves, M.D.

913-362-1600DeanReevesMD@gmail.com

NW Regen

Recruiting

Portland, Oregon, United States, 97210

Contacts

Ryan R Wood, N.D., D.C.

503-799-6115libby@nwregen.com

Kenneth D Reeves, M.D.

913-362-1600DeanReevesMD@gmail.com

Paul Johnson, MD.

Recruiting

Portland, Oregon, United States, 97210

Contacts

Paul W Johnson, D.O.

(412) 596-2606paulwjohnsonDO@yahoo.com

Kenneth D Reeves, M.D.

913-362-1600DeanReevesMD@gmail.com

Medical Procedures of Wisconsin

Recruiting

Madison, Wisconsin, United States, 53709

Contacts

Eric Phillippi, M.D.

(262) 844-9123eric@medicalprocedures.com

Kenneth D Reeves, M.D.

913-362-1600DeanReevesMD@gmail.com

More Information

Sponsor

Dr. Dean Reeves Clinic

Last update posted

Sep 16, 2026

Last verified

Sep, 2026

Keywords

  • Dextrose
  • Hydrodissection
  • Cervical Plexus

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-02. This information was provided to ClinicalTrials.gov by Dr. Dean Reeves Clinic on 2026-09-16. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.