Recruiting

Audio Therapy

Sponsor:

UCLA

Code:

NCT07390487

Conditions

Psoriasis (PsO)

Anxiety

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Music Therapy

Pink Noise

Study Details

Brief summary:

Anxiety in psoriasis is associated with impaired quality of life, and the prevalence of anxiety symptoms in psoriatic populations is approximately 34% and anxiety disorders up to 16%. Many experts recommend routine screening, referral, and interventions for anxiety in psoriasis; however, many barriers inhibit access to mental health resources and proper management. To our knowledge, there is a lack of easily accessible interventions that manage anxiety. Audio-based therapy offers convenient and effective interventions that show reduced anxiety in published, randomized studies and is a promising management for psoriasis patients. This study will evaluate the effects of audio therapy in patients with psoriasis and measure changes in overall symptoms.

Conditions

Psoriasis (PsO)

Anxiety

Study ID

NCT07390487

Start date

Feb 1, 2026

Status verified date

Jul, 2026

Completion date

Dec, 2027

Anticipated

Primary completion date

Dec, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age ≥18 years
  • Self-reported dermatologist-diagnosed psoriasis
  • GAD 2-Item Score ≥1 at screening
  • Ability to consent and complete pre- and post-intervention surveys.
  • Internet access and the ability to use a computer/smartphone with headphones for a single 23-30 minute session at home.

Exclusion Criteria:

  • Severe hearing impairment precluding headphone listening
  • Any condition requiring strict sound avoidance (such as seizure/epilepsy, major head trauma, severe sound-triggered migraine) that would make participation unsafe.
  • Other diagnoses that in the investigator's judgment preclude safe participation or interfere with anxiety or psoriasis evaluation.

Study Design

Enrollment

120 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Music Therapy

Participants listen to the iso-principle music with added auditory beat stimulation playlist for 23-30 minutes.

sham comparator: Pink Noise

Participants listen to the pink noise playlist for 23-30 minutes.

Interventions

Music Therapy

Participants listen to the iso-principle music with added auditory beat stimulation playlist for 23-30 minutes.

Pink Noise

Participants listen to the pink noise playlist for 23-30 minutes.

Primary outcome measure

  • Anxiety: State Trait Inventory for Cognitive and Somatic Anxiety (STICSA) [ Time Frame: From the pre-intervention survey to the post-intervention survey, approximately 30 minutes. ]

Central Contacts and Locations

Central contacts

Amélie Spangenberg, Psoriasis Clinical Research Fellow, MBBS

415-944-7618amelie.spangenberg@ucsf.edu

Locations

Liao Lab at UCSF

Recruiting

San Francisco, California, United States, 94115

Contacts

Amélie Spangenberg, Psoriasis Clinical Research Fellow, MBBS

415-944-7618amelie.spangenberg@ucsf.edu

Principal Investigator:

Wilson Liao, MD

More Information

Sponsor

University of California, San Francisco

Last update posted

Jul 23, 2026

Last verified

Jul, 2026

Keywords

  • Surveys and Questionnaires
  • Acoustic Stimulation
  • Complementary Therapies

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-28. This information was provided to ClinicalTrials.gov by University of California, San Francisco on 2026-07-23. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.