Recruiting

Biomotum

Sponsor:

University of Nebraska

Code:

NCT07393971

Conditions

Healthy Young Adults

Eligibility Criteria

Sex: All

Age: 19 - 35

Healthy Volunteers: Accepted

Interventions

Adaptive Torque Control System for Ankle Exoskeleton

Study Details

Brief summary:

This study is developing and testing a new controller for a robotic ankle exoskeleton (Biomotum) that can adjust itself in real time to better support people while they walk. The system learns how each person moves and automatically changes the amount and timing of assistance to make walking feel easier and more efficient. By using information from the person wearing the device, the exoskeleton can quickly find the level of support that works best for them. The long-term goal is to create personalized walking assistance that can help people with mobility limitations move more comfortably and with less effort.

Conditions

Healthy Young Adults

Study ID

NCT07393971

Start date

Aug 15, 2026

Status verified date

Dec, 2025

Completion date

Dec, 2028

Anticipated

Primary completion date

Aug, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 19 - 35

Healthy Volunteers: Accepted

Inclusion Criteria:

  • able to walk independently on a treadmill for 10 minutes,
  • free of neurological, cardiovascular, pulmonary, or musculoskeletal conditions that limit walking and exercising,
  • no current lower extremity pain or injury,
  • able to wear an exoskeleton and safety harness, can provide informed consent

Exclusion Criteria:

  • history of neurological disease that affected gait or balance,
  • current or recent lower extremity musculoskeletal injury or surgery,
  • chronic lower extremity pain during walking,
  • inability to participate in moderate-intensity exercise,
  • require an assistive device for walking,
  • any metabolic or systemic diseases that may be exacerbated by exercise

Study Design

Enrollment

6 participants

Anticipated

Intervention Model

Single group

Primary purpose

Device Feasibility

Interventions and Outcome Measures

Arms

experimental: Single-Arm Study of a Personalized Robotic Ankle Exoskeleton Controller

This arm employs a within-subject design with two methods of estimating metabolic cost versus the gold standard measure of metabolic cost, wherein a single participant is subjected to two distinct measurements. This design allows for a direct comparison of the effects of each method (i.e., estimation versus gold standard) within the same individual, minimizing intersubject variability and enhancing the statistical power of the analysis.

Interventions

Adaptive Torque Control System for Ankle Exoskeleton

This intervention uses a robotic ankle exoskeleton equipped with a real-time adaptive controller that adjusts plantarflexion torque based on each participant's walking mechanics. Unlike standard exoskeleton controllers that use fixed or pre-programmed assistance levels, this system employs human-in-the-loop optimization to continuously update torque magnitude and timing during treadmill walking. The controller integrates metabolic estimations, kinematic data, and musculoskeletal modeling to identify individualized assistance patterns that reduce walking effort and improve muscle activation efficiency. Participants complete multiple walking trials while the controller automatically modifies assistance to determine the optimal personalized settings.

Primary outcome measure

  • Successful Real-Time Operation of the Robotic Ankle Exoskeleton Controller [ Time Frame: through study completion, an average of 1 year ]

Central Contacts and Locations

Central contacts

Locations

Biomechanics Research Building, University of Nebraska at Omaha

Recruiting

Omaha, Nebraska, United States, 68108

Contacts

Principal Investigator:

Farah Fallahtafti, PhD

More Information

Sponsor

University of Nebraska

Last update posted

Nov 6, 2026

Last verified

Dec, 2025

Keywords

  • robotic ankle exoskeleton
  • human-in-the-loop optimization
  • wearable robotics
  • musculoskeletal modeling
  • muscle activation analysis

Trial information was received from ClinicalTrials.gov and was last updated on 2026-11-08. This information was provided to ClinicalTrials.gov by University of Nebraska on 2026-11-06. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.