Recruiting

Peer Support Specialists

Sponsor:

Johns Hopkins University

Code:

NCT07397598

Conditions

Alcohol Use Disorder

Alcohol Related Liver Disease

Liver Transplant Recipient

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Peer Support

Study Details

Brief summary:

Liver transplant (LT) recipients with a history of alcohol-related liver disease (ALD) may encounter various psychosocial and medical challenges during post-LT recovery, even beyond the initial post-transplant period. Effective and sustainable interventions will be crucial for improving patient outcomes. This clinical trial will examine the impact of peer support specialists (PSS) on the recovery experience of individuals who received LT for ALD. The trial seeks to answer two main questions:

  • Are LT recipients who work with PSS less likely to resume alcohol use or tend to drink less overall?
  • Do LT recipients who work with PSS engage more with recommended medical care and have better overall survival?

Conditions

Alcohol Use Disorder

Alcohol Related Liver Disease

Liver Transplant Recipient

Study ID

NCT07397598

Start date

Oct, 2026

Status verified date

Oct, 2026

Completion date

Jun, 2029

Anticipated

Primary completion date

Jun, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • English speakers
  • Received a liver transplant for alcohol-associated liver disease
  • Has 1 to 3 years of continuous alcohol abstinence at the time of trial entry

Exclusion Criteria:

  • Liver transplant recipients without a history of alcohol-associated liver disease
  • Inability to provide informed consent
  • Active participation in a separate intervention trial for alcohol use disorder

Study Design

Enrollment

95 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Peer Support Specialist (PSS)

Interventions

Peer Support

The study will recruit PSS based on lived experiences with ALD/LT and interpersonal skills. The PSS will receive tailored skills training from the study team in areas such as delivering brief counseling, active listening, and maintaining confidentiality.

Participants will meet regularly with a PSS between standard clinic visits throughout a one-year study period. The PSS will deliver brief counseling interventions at each session. Study investigators will meet with the PSS at scheduled intervals to review progress. Study investigators will also review up to 20% of the audio recordings of sessions between PSS and study participants to assess fidelity to the intervention protocol.

Primary outcome measure

  • Alcohol Consumption [ Time Frame: Up to 1 year ]

Central Contacts and Locations

Central contacts

Po-Hung Chen, MD, PhD

410-550-1793pchen37@jhmi.edu

Mary E. McCaul, PhD

410-955-9526mmccaul1@jhmi.edu

Locations

Johns Hopkins University School of Medicine

Recruiting

Baltimore, Maryland, United States, 21287

Contacts

Po-Hung Chen, MD, PhD

410-550-1793pchen37@jhmi.edu

Mary E. McCaul, PhD

410-955-9526mmccaul1@jhmi.edu

More Information

Sponsor

Johns Hopkins University

Last update posted

Oct 6, 2026

Last verified

Oct, 2026

Keywords

  • Alcohol use disorder
  • Alcohol Related Liver Disease
  • Liver transplant recipient
  • Peer support specialist

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-07. This information was provided to ClinicalTrials.gov by Johns Hopkins University on 2026-10-06. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.