Recruiting

Observational Study

Sponsor:

Brown University

Code:

NCT07398443

Conditions

Behavioral Economics

Cannabis Smoking

Tobacco Smoking

Eligibility Criteria

Sex: All

Age: 18 - 25

Healthy Volunteers: Accepted

Interventions

Cue Reactivity

Study Details

Brief summary:

The multi session experimental study aims to determine dual use patterns of marijuana and tobacco by assessing the impact of price and availability of marijuana and tobacco using a cross price elasticity of demand task. The study will recruit 120 non-treatment seeking emerging young adults (18-25 years) who smoke marijuana and tobacco.

Conditions

Behavioral Economics

Cannabis Smoking

Tobacco Smoking

Study ID

NCT07398443

Start date

Feb 17, 2026

Status verified date

Mar, 2026

Completion date

Nov 30, 2028

Anticipated

Primary completion date

Nov 30, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 25

Healthy Volunteers: Accepted

Inclusion Criteria:

1. Males/females who are 18 to 25 years of age
2. Young adults who currently smoke commercial tobacco cigarettes (≥1x weekly in the past 30 days and for the past six months)
3. Young adults who currently smoke marijuana (≥4 times in past 30 days and at least weekly on average for the last six months)
4. Participants must report purchasing their own tobacco and marijuana at least once in the past 6 months
5. Participants must speak, comprehend, and read English.

Exclusion Criteria:

1. Intention to quit marijuana or tobacco use in the next 30 days
2. Self-reported illicit drug or heavy episodic alcohol use on >20 days in the past month (excluding marijuana)
3. Individuals who are pregnant or breastfeeding
4. Positive saliva test for recent THC use
5. Breath alcohol level above 0 at any session.
6. Participants who exclusively roll their own tobacco cigarettes

Study Design

Enrollment

120 participants

Anticipated

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Cue Reactivity

Participants will be exposed to neutral followed by cannabis or tobacco cues in a fixed sequence while they answer questions about their subjective state. The cues will include everyday items (e.g., eraser) and cannabis-related items (e.g., lighter).

Interventions

Cue Reactivity

Participants will be exposed to neutral followed by cannabis or tobacco cues in a fixed sequence while they answer questions about their subjective state. The cues will include everyday items (e.g., eraser) and cannabis-related items (e.g., lighter).

Primary outcome measure

  • Change in self-reported cannabis craving [ Time Frame: Up to 40 days post-baseline session ]
  • Change in self-reported tobacco craving [ Time Frame: Up to 40 days post-baseline session ]

Central Contacts and Locations

Central contacts

Elizabeth Aston, PhD

401-863-6668elizabeth_aston@brown.edu

Locations

Brown University School of Public Health

Recruiting

Providence, Rhode Island, United States, 02903

Contacts

Elizabeth Aston, PhD

401-863-6668elizabeth_aston@brown.edu

More Information

Sponsor

Brown University

Last update posted

Mar 4, 2026

Last verified

Mar, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Brown University on 2026-03-04.