Recruiting

ROCKS

Sponsor:

University of Illinois at Chicago

Code:

NCT07428278

Conditions

Advanced Cancer

End of Life

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

ROCKS

Usual Care

Study Details

Brief summary:

The aims of this study are to (1) assess the feasibility, acceptability, and usability of the ROCKS intervention among patients with advanced cancer and their family caregivers through a randomized controlled trial in a cancer center setting; (2) evaluate the preliminary efficacy of ROCKS, as compared to usual care, on changes in completion of advance directives; and (3) explore the dyadic effects of resilience on self-efficacy, optimism, dyadic communication and coping, anxiety, and depression using an actor-partner interdependence model.

Conditions

Advanced Cancer

End of Life

Study ID

NCT07428278

Start date

May 28, 2026

Status verified date

Feb, 2026

Completion date

Jul 31, 2028

Anticipated

Primary completion date

May 31, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Eligible patients will (1) be ≥ 18 years of age; (2) be diagnosed with stage 3 or 4 cancer; and (3) have a family caregiver who is willing to participate.
  • Eligible family caregivers will be ≥ 18 years of age. All participants must be able to read, write, and speak English with minimal assistance from others and have access to the internet on a smartphone, laptop, or computer.

Exclusion Criteria:

  • Patient participants will be ineligible if they have (1) a Short Portable Mental Status Questionnaire (SPMSQ) score < 8; or (2) have completed any form of advance directive.

Study Design

Enrollment

152 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: ROCKS

Participants assigned to this arm will receive a web-based resilience-building intervention.

active comparator: Usual Care

Participants assigned to this arm will receive an advance directive called Five Wishes.

Interventions

ROCKS

The intervention will be provided to participants to strengthen optimism, communication skills, knowledge, and self-efficacy to support patients and family caregivers in engaging in advance care planning discussions.

Usual Care

An advance directive called Five Wishes will be provided to participants to increase their knowledge about advance care planning.

Primary outcome measure

  • Completion of advance directives [ Time Frame: Week 8 ]

Central Contacts and Locations

Central contacts

Li-Ting Longcoy

312-996-3024liting@uic.edu

Locations

University of Illinois Chicago

Recruiting

Chicago, Illinois, United States, 60607

Contacts

Li-Ting H. Longcoy

312-996-3024liting@uic.edu

More Information

Sponsor

University of Illinois at Chicago

Last update posted

Jun 9, 2026

Last verified

Feb, 2026

Keywords

  • Resilience
  • Advance Care Planning

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Illinois at Chicago on 2026-06-09.