Recruiting

Observational Study

Sponsor:

Concordia University Wisconsin

Code:

NCT07429370

Conditions

Inactivity, Physical

Eligibility Criteria

Sex: All

Age: 18 - 30

Healthy Volunteers: Accepted

Interventions

Decreased step count

Study Details

Brief summary:

Exercise can reduce the risk of several chronic diseases. However, recent studies have suggested sitting for too long before exercising can decrease exercise benefits. This study will help determine why this may occur.

Conditions

Inactivity, Physical

Study ID

NCT07429370

Start date

Jan 1, 2026

Status verified date

Feb, 2026

Completion date

Dec 31, 2026

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 30

Healthy Volunteers: Accepted

Inclusion Criteria:

  • • between the ages of 18-30 years old

Exclusion Criteria:

  • • free from acute or chronic illness (cardiac, pulmonary, liver, or kidney abnormalities, cancer, uncontrolled hypertension, insulin- or non-insulin dependent diabetes or other known metabolic disorders)

  • do not take medications related to metabolism (i.e., statins, metformin, GLP-1 agonists)
  • free from orthopedic limitations (including any artificial joints)
  • currently smoke or participate in other forms of tobacco use.

Study Design

Enrollment

6 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

active comparator: >8,500 steps the day prior to exericse

experimental: <5,000 steps the day prior to exercise

Interventions

Decreased step count

Subjects will walk less than 5,000 steps

Primary outcome measure

  • Concentration of metabolites within the plasma [ Time Frame: Participants will complete the study within 6 weeks of enrollment. ]
  • Concentration of proteins within the plasma [ Time Frame: Participants will complete the study within 6 weeks of enrollment. ]

Central Contacts and Locations

Central contacts

Kevin J Gries, PhD

2622434293kevin.gries@cuw.edu

Locations

Concordia University of Wisconsin

Recruiting

Mequon, Wisconsin, United States, 53093

Contacts

Kevin J Gries, PhD

2622434293kevin.gries@cuw.edu

More Information

Sponsor

Concordia University Wisconsin

Last update posted

Feb 24, 2026

Last verified

Feb, 2026

Keywords

  • Exercise
  • Metabolism

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Concordia University Wisconsin on 2026-02-24.