Recruiting

Pelvic Floor Physical Therapy

Sponsor:

University of Cincinnati

Code:

NCT07447895

Conditions

Cervical Cancer

Radiation Therapy Complication

Pelvic Floor Disorders

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Pelvic floor physical therapy

Study Details

Brief summary:

This is a single arm phase II study in which 28 patients who will be undergoing definitive pelvic external beam radiation therapy for cervical cancer will receive pelvic floor physical therapy 4 weeks after completing radiation therapy.

Conditions

Cervical Cancer

Radiation Therapy Complication

Pelvic Floor Disorders

Study ID

NCT07447895

Start date

Apr 16, 2026

Status verified date

Apr, 2026

Completion date

Apr 16, 2030

Anticipated

Primary completion date

Apr 16, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Participants must be female.
2. Patients must be 18 years old or older.
3. Any patient with invasive cervical cancer who is planned for definitive chemoradiation.
4. Plan to receive a minimum dose of 45Gy to pelvis per investigator.
5. Willing to undergo pelvic floor physical therapy.

Exclusion Criteria:

1. Any previous therapeutic pelvic radiation.
2. Non-English speaking.

Study Design

Enrollment

28 participants

Anticipated

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Pelvic floor physical therapy

Patients who will be undergoing definitive pelvic external beam radiation therapy for cervical cancer will receive pelvic floor physical therapy 4 weeks after completing radiation therapy.

Interventions

Pelvic floor physical therapy

Four weeks after completion of RT, patients will begin a standardized pelvic floor PT course. The protocol will include two 1-hour physical therapy appointments focused on pelvic floor muscle training, dilator training and education. These sessions will be 4 weeks apart and performed by a pelvic floor physical therapist.

Primary outcome measure

  • Evaluate fecal incontinence via EORTC-QLQ CX24 validated survey [ Time Frame: 3 months after Radiation Therapy Treatment ]

Central Contacts and Locations

Central contacts

UCCC Clinical Trials Office

513-584-7698cancer@uchealth.com

Locations

University of Cincinnati

Recruiting

Cincinnati, Ohio, United States, 45219

More Information

Sponsor

University of Cincinnati

Last update posted

Apr 23, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Cincinnati on 2026-04-23.