Recruiting

Continuous Glucose Monitoring

Sponsor:

UCLA

Code:

NCT07449039

Conditions

Gestational Diabetes Mellitus in Pregnancy

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Continuous Glucose Monistor

Study Details

Brief summary:

This is a pilot study designed to evaluate the effectiveness of continuous glucose monitoring (CGM) within hours of delivery to predict long-term risk of Type 2 Diabetes Mellitus in patients diagnosed with gestational diabetes.

Participants will be provided a CGM within 2 hours after delivery and wear the device for 24 hours. Participants will be instructed to peel off the device after 24 hours. Participants will also be asked to complete two surveys regarding their experience at 1-3 months postpartum and 12-14 months postpartum.

Conditions

Gestational Diabetes Mellitus in Pregnancy

Study ID

NCT07449039

Start date

Sep 28, 2025

Status verified date

Feb, 2026

Completion date

Jun, 2030

Anticipated

Primary completion date

Dec, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Prenatal care at UCLA Health
  • Planning to deliver at UCLA Ronald Reagan or UCLA Santa Monica
  • Confirmed gestational diabetes diagnosis based on 2-step approach
  • Maternal age >= 18 years

Exclusion Criteria:

  • Pre-gestational diabetes (T1DM or T2DM)
  • Multifetal gestation
  • Intra-amniotic infection by clinical criteria
  • Postpartum hemorrhage
  • Maternal ICU admission
  • Known allergy to medical-grade adhesive
  • Presence of skin lesions at anticipated CGM application site
  • Scheduled postpartum non-sonographic imaging study (radiograph, magnetic resonance imaging (MRI), or computed tomography (CT) scan) during trial
  • Metformin use
  • Steroid use
  • Terbutaline use within 4 hours of delivery
  • Cystic fibrosis
  • MODY (mature onset of diabetes in the young)

Study Design

Enrollment

50 participants

Anticipated

Intervention Model

Single group

Primary purpose

Other

Interventions and Outcome Measures

Arms

other: Continuous Glucose Monitor

Administration of a Continuous Glucose Monitor within 2 hours after delivery for 24-hour collection of glycemic data.

Interventions

Continuous Glucose Monistor

Continuous glucose monitoring sensor that provides 24/7 detailed glycemic information. Participants will wear for 24 hours and then be instructed to peel off.

Primary outcome measure

  • Clinical Efficacy Associated with CGM use immediately postpartum as compared to the 2 hr Glucose tolerance test [ Time Frame: 24 hours postpartum and 1-3 months postpartum ]
  • Clinical Efficacy Associated with CGM use immediately postpartum as compared to the HbA1c test postpartum [ Time Frame: 24 hours postpartum and 1-3 months postpartum ]

Central Contacts and Locations

Central contacts

Rujuta Sathe

310-794-8893RSathe@mednet.ucla.edu

Dana Levin-Lopez, MPH

310-794-8893dlevinlopez@mednet.ucla.edu

Locations

University of California, Los Angeles

Recruiting

Los Angeles, California, United States, 90095

Contacts

Dana Levin-Lopez, MPH

310-794-8893dlevinlopez@mednet.ucla.edu

More Information

Sponsor

University of California, Los Angeles

Last update posted

Mar 4, 2026

Last verified

Feb, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of California, Los Angeles on 2026-03-04.