Recruiting

Cancer Education

Sponsor:

Memorial Sloan Kettering Cancer Center

Code:

NCT07454330

Conditions

Cancer

Survivorship

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Cancer Education

Meaning-Centered Counseling

Peer Support

Enhanced Standard Care

Study Details

Brief summary:

The purpose of this study is to evaluate different combinations of cancer education sessions, counseling sessions, and peer support meetings developed for Chinese cancer patients and survivors. The researchers will look at whether the combinations are practical and effective, and how they impact participants' quality of life.

Conditions

Cancer

Survivorship

Study ID

NCT07454330

Start date

Feb 27, 2026

Status verified date

Aug, 2026

Completion date

Feb, 2028

Anticipated

Primary completion date

Feb, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Diagnosed with cancer (any type/stage) (per EMR for MSK patients or self-report for external participants) within the last 5 years
  • Age ≥ 18 years (per EMR for MSK patients or self-report for external participants)

Self-Report Criteria:

  • Of Chinese descent
  • Speaks Mandarin "well" or "very well"
  • Moderately low HRQOL (<70 FACT-G score)4, 48
  • Resides in New York or New Jersey
  • Agrees to participate via telehealth (video or phone)
  • Agrees to be audio-recorded

Exclusion Criteria:

Self-Report Criteria:

  • Per PI determination, requires a higher level of care for current passive or active suicidal ideation than current protocol is able to provide. If a participant receives a score of > 0 on item 9 of the PHQ-9,5 they will be referred to study PI for further evaluation using the Columbia-Suicide Severity Rating Scale. They will be excluded from participation in this study if there is presence of suicidal risk, determined by affirmative response(s) on the Columbia-Suicide Severity Rating Scale (C-SSRS)
  • Too ill to participate determined by the question: "Do you feel too ill to participate because of communication problems, uncontrollable pain, or other symptoms that prevent you from participating?"
  • Cognitive impairment (Montreal Cognitive Assessment 5 Minute - telephone version with a score < 12)
  • Per consenting professional determination, unable to understand the informed consent procedure
  • Participation in study #14-076: Adaptation of Individual Meaning-Centered Psychotherapy for Chinese immigrant cancer patients)
  • Currently receiving/have received psychotherapy/counseling/peer support within the last 6 months (patients being treated solely with psychotropic medications will not be excluded if they are not receiving psychotherapy/counseling/peer support)

Study Design

Enrollment

64 participants

Anticipated

Allocation

Randomized

Intervention Model

Factorial

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: 1 - Cancer Education + Meaning-Centered Counseling + Peer Support + Enhanced Standard Care

All participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions.Counseling sessions, will have 3 weekly sessions. Peer support meetings, will have 3 monthly meetings.

experimental: 2 - Cancer Education + Meaning-Centered Counseling + Enhanced Standard Care

All participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions.Counseling sessions, will have 3 weekly sessions.

experimental: 3 - Cancer Education + Peer Support + Enhanced Standard Care

All participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions. Peer support meetings, will have 3 monthly meetings.

experimental: 4 - Cancer Education + Enhanced Standard Care

All participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions.

experimental: 5 - Meaning-Centered Counseling + Peer Support + Enhanced Standard Care

All participants will also receive cancer information materials and resources.Counseling sessions, will have 3 weekly sessions. Peer support meetings, will have 3 monthly meetings

experimental: 6 - Meaning-Centered Counseling- + Enhanced Standard Care

All participants will also receive cancer information materials and resources. Counseling sessions, will have 3 weekly sessions.

experimental: 7 - Peer Support + Enhanced Standard Care

All participants will also receive cancer information materials and resources. Peer support meetings, will have 3 monthly meetings

active comparator: 8 - Enhanced Standard Care

All participants will also receive cancer information materials and resources.

Interventions

Cancer Education

Cancer Education on side effects and their management, treatment options, advance care planning, and survivorship. Each session will last about 30-60 minutes and will be completed over the phone or by video call.

Meaning-Centered Counseling

Meaning-centered counseling aims to activate culturally relevant meaning-focused coping strategies in Chinese-speaking patients and survivors (CCS). Each session will last about 45-60 minutes and will be completed over the phone or by video call.

Peer Support

Peer support aims to increase social support for CCS to decrease cancer stigma, which has been associated with greater psychological distress, especially among less acculturated Chinese immigrant CCS. The meetings will include up to 6-8 Mandarin-speaking patients and survivors and will last about 90 minutes.

Enhanced Standard Care

enhanced standard care ( written cancer information materials in Chinese and referral to counseling)

Primary outcome measure

  • Proportion of eligible participants who enroll in the trial. [ Time Frame: 2 years ]
  • Proportion of participants who complete treatment [ Time Frame: 24 weeks ]

Central Contacts and Locations

Central contacts

Florence Lui, PhD

646-888-8375luif@mskcc.org

Jennifer Leng, MD, MPH

646-888-8057

Locations

Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

Recruiting

Basking Ridge, New Jersey, United States, 07920

Contacts

Florence Lui, PhD

646-888-8375

Memorial Sloan Kettering Monmouth (All Protocol Activities)

Recruiting

Middletown, New Jersey, United States, 07748

Contacts

Florence Lui, PhD

646-888-8375

Memorial Sloan Kettering Bergen (All Protocol Activities)

Recruiting

Montvale, New Jersey, United States, 07645

Contacts

Florence Lui, PhD

646-888-8375

Memorial Sloan Kettering Cancer Center Suffolk- Commack (All Protocol Activities)

Recruiting

Commack, New York, United States, 11725

Contacts

Florence Lui, PhD

646-888-8375

Memorial Sloan Kettering Westchester (All Protocol Activities)

Recruiting

East White Plains, New York, United States, 10604

Contacts

Florence Lui, PhD

646-888-8375

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

Recruiting

New York, New York, United States, 10065

Contacts

Florence Lui, PhD

646-888-8375

Jennifer Leng, MD, MPH

646-888-8057

Principal Investigator:

Florence Lui, PhD

Memorial Sloan Kettering Nassau (All Protocol Activities)

Recruiting

Uniondale, New York, United States, 11553

Contacts

Florence Lui, PhD

646-888-8375

More Information

Sponsor

Memorial Sloan Kettering Cancer Center

Last update posted

Aug 13, 2026

Last verified

Aug, 2026

Keywords

  • Chinese
  • Quality of Life
  • Patients
  • Survivors
  • 26-025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Memorial Sloan Kettering Cancer Center on 2026-08-13.