Recruiting

Observational Study

Sponsor:

Yale University

Code:

NCT07457567

Conditions

Live Face Processing in Typically Developed Participants

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Transcranial Magnetic Stimulation (TMS)

Study Details

Brief summary:

This study aims to understand the neural mechanisms that underlie synchronization of two brains during social interactions.

Conditions

Live Face Processing in Typically Developed Participants

Study ID

NCT07457567

Start date

Nov 3, 2025

Status verified date

Jul, 2026

Completion date

Jul 31, 2028

Anticipated

Primary completion date

Jul 31, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

-Self reported typically developed adults.

Exclusion Criteria:

-No prior history of seizure activity. Self reported absence of recreational drugs at time of study.

Study Design

Enrollment

50 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

sham comparator: Sham Comparator

TMS to a non-targeted region.

experimental: Experimental Comparator

TMS to targeted regions

Interventions

Transcranial Magnetic Stimulation (TMS)

TMS to targeted regions. Transcranial Direct Current Stimulation, tDCS, to targeted and sham regions.

Primary outcome measure

  • Percent change in hemodynamic signals [ Time Frame: Baseline and At time of measurement, approximately one hour ]
  • Electroencephalography (EEG) response to live face gaze [ Time Frame: At time of measurement, approximately one hour ]
  • Eye Contact Behavior [ Time Frame: At time of measurement, approximately one hour ]
  • Face Gaze Behavior [ Time Frame: At time of measurement, approximately one hour ]

Central Contacts and Locations

Central contacts

Joy Hirsch, PhD

9174947768joy.hirsch@yale.edu

Locations

Yale School of Medicine

Recruiting

New Haven, Connecticut, United States, 06511

Contacts

Joy Hirsch, PhD

917-494-7768joy.hirsch@yale.edu

More Information

Sponsor

Yale University

Last update posted

Jul 13, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Yale University on 2026-07-13.