Recruiting

Cognitive Control & Memory

Sponsor:

Florida International University

Code:

NCT07468279

Conditions

Cognitive Control

Memory

Eligibility Criteria

Sex: All

Age: 18 - 59

Healthy Volunteers: Accepted

Interventions

Sham device

STARSTIM Device in-phase

STARSTIM Device anti-phase

Study Details

Brief summary:

This study aims to clarify relations between brain oscillations and two cognitive functions: cognitive control and memory.

Conditions

Cognitive Control

Memory

Study ID

NCT07468279

Start date

Mar 13, 2026

Status verified date

Aug, 2026

Completion date

Jan, 2031

Anticipated

Primary completion date

Jan, 2031

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 59

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 18 years and older
  • Fluent in English
  • Normal or corrected-to-normal vision
  • Willing to be photographed

Exclusion Criteria:

  • Must not have ever had an injury to the head that's caused you to be knocked out for a period of time (e.g., from a fall, blow to the head, road traffic accident).
  • Must not have an uncorrected vision or physical disability that interferes with your ability to see stimuli presented briefly on a computer screen or click a mouse button rapidly.
  • Must not have a history of epilepsy, convulsions, or seizures (except childhood febrile seizures).
  • Must not have a history of fainting or syncope.
  • For female participants, they must not be pregnant and/or must not think they might be pregnant.
  • Must not have skin problems like eczema, dermatitis, or open wounds on the scalp.
  • Must not have had prior brain surgery.
  • Must not have any metal located in the head/neck (except for dental work i.e., braces, permanent retainers, etc.)
  • Must not have any devices or other implants located in/near their head. This includes cochlear implants and aneurysm clips, cardiac pacemaker, or any other implanted electronic device.
  • Must not have a current (active) alcohol or substance use disorder, must have no recent history of withdrawal symptoms, and must be able to safely abstain from alcohol and non-prescribed/illicit drugs for at least 24 hours before the session.
  • Must not have any alcohol on the day of the session, must limit alcohol consumption to no more than 2 drinks (if legally permitted) in the prior 24 hours, and must not use any non-prescribed or illicit drugs in the 24 hours before the session.
  • Must not be sick with a fever, sleep-deprived, or feel dizzy, unwell, or intoxicated.
  • Must also have eaten and had fluids but not have consumed more caffeine than they typically consume.
  • Must not be taking anticonvulsant/anti-epileptic drugs or have ever taken them within their lifetime.
  • Must not be taking benzodiazepines or have taken them within the past 3 months.
  • Must not have had a recent change (start, stop, dose change) for any psychiatric/psychotropic medications within the past 3 months.
  • Must not be taking Bupropion (Wellbutrin, Zyban), Tricyclic antidepressants (e.g., amitriptyline, imipramine, clomipramine, etc.), Antipsychotics (clozapine; chlorpromazine, haloperidol, etc.), or Tramadol or have taken them within the past 3 months.
  • Must not have experienced cardiac problems, fibrillation, or have taken medications associated with cardiac conditions within the past 3 months.
  • Must not meet the diagnostic threshold for Autism Spectrum Disorder, Intellectual Disability, or Psychotic Disorders.

Study Design

Enrollment

90 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

sham comparator: Sham Stimulation

Participants will be randomized to receive an active STARSTIM treatment or sham treatment.

experimental: STARSTIM device treatment (in-phase theta)

Participants will be randomized to receive an active STARSTIM treatment or sham treatment.

experimental: STARSTIM device treatment (anti-phase stimulation)

Participants will be randomized to receive an active STARSTIM treatment or sham treatment.

Interventions

Sham device

Intervention which uses an inactive form of stimulation via electrodes on the scalp.

STARSTIM Device in-phase

Intervention that uses the Starstim tES device to introduce transcranial alternating current stimulation (tACS) in the form of in-phase theta (\~3.5 to \~7.5 Hz) via electrodes on the scalp.

STARSTIM Device anti-phase

Intervention that uses the Starstim tES device to introduce transcranial alternating current stimulation (tACS) in the form of anti-phase stimulation via electrodes on the scalp.

Primary outcome measure

  • The Difference Between Incidental Memory of Faces on Error versus Correct Trials from Baseline to Post Brain Stimulation [ Time Frame: Baseline through study visit completion, a maximum of 3 hours ]

Central Contacts and Locations

Locations

Florida International University

Recruiting

Miami, Florida, United States, 33199

Contacts

George Buzzell

305-348-2868gbuzzell@fiu.edu

More Information

Sponsor

Florida International University

Last update posted

Aug 27, 2026

Last verified

Aug, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Florida International University on 2026-08-27.