Recruiting
Phase 1

SBT with VR

Sponsor:

University of Calgary

Code:

NCT07469163

Conditions

Subacute Stroke

Stroke

Stroke (Subacute)

Stroke Gait Rehabilitation

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Split-Belt Treadmill

Study Details

Brief summary:

After experiencing a stroke, many individuals encounter difficulties with walking and balance, which can significantly impact their independence. Recent studies have indicated that split-belt treadmill (SBT) training is effective for improving gait metrics, including walking speed and step length asymmetry. The SBT allows each leg to move at different speeds, which has been shown to help chronic stroke survivors learn to walk more symmetrically. However, there is limited knowledge about the dose participants should receive and the safety of SBT training in the early stages of recovery, which is a crucial period for rehabilitation. To address this gap, we are evaluating an innovative SBT with virtual reality (VR) features at the Foothills Medical Center. Our objective is to conduct a study to determine the amount of SBT training patients can tolerate in a day. In this study, stroke survivors will engage in a series of walking exercises on the SBT. We will escalate the duration of SBT walking until participants reach a point where they can no longer continue due to dose-limiting criteria such as fatigue or discomfort. The findings from this initial phase will guide future larger trials to explore the effectiveness of this training method. Ultimately, we aspire to improve rehabilitation strategies for stroke survivors, assisting them in regaining mobility and enhancing their quality of life more effectively.

Conditions

Subacute Stroke

Stroke

Stroke (Subacute)

Stroke Gait Rehabilitation

Study ID

NCT07469163

Start date

Mar 1, 2026

Status verified date

Mar, 2026

Completion date

Aug 31, 2026

Anticipated

Primary completion date

Aug 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Ischemic or hemorrhagic stroke survivors
  • First stroke
  • Over 18 years old
  • Between one week and three months post-stroke
  • can understand task instructions.

Exclusion Criteria:

  • History of significant neurological diseases (e.g. Multiple Sclerosis, Parkinson's disease)
  • Orthopedic issues in lower extremities (e.g. severe knee Osteoarthritis)
  • Excessive pain preventing participants from participating in treadmill-based activities
  • Cerebellar stroke
  • Body weight more than 560 lbs (this exceeds the weight limit of the support harness)

Study Design

Enrollment

72 participants

Anticipated

Intervention Model

Sequential

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: Intervention - Dose Escalation

Participants enrolled into split-belt treadmill dose currently being tested

Interventions

Split-Belt Treadmill

Participants undertake 5 days of treadmill walking. Each day is broken into 3 episodes: A) two-minutes tied-belt walking, B) n minutes split-belt walking (dose escalating component), C) 10-minutes tied-belt walking. Split-belt walking will start at a dose of 8-minutes and escalate by 3 minute increments, up to a maximum dose of 30 minutes.

Primary outcome measure

  • Dose Tolerability [ Time Frame: 5 days ]

Central Contacts and Locations

Central contacts

Locations

Foothills Hospital

Recruiting

Calgary, Alberta, Canada, T2N2T9

Contacts

More Information

Sponsor

University of Calgary

Last update posted

Mar 13, 2026

Last verified

Mar, 2026

Keywords

  • stroke
  • subacute stroke
  • split belt treadmill
  • gait rehabilitation
  • stroke recovery

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Calgary on 2026-03-13.