Recruiting

Observational Study

Sponsor:

Arizona State University

Code:

NCT07476053

Conditions

Migraine Headache

Sleep

Photophobia

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Ambient Lighting Condition

Study Details

Brief summary:

The purpose of this study is to examine the relationship between daily light exposure patterns, sleep quality, and migraine characteristics in adults with migraine, with and without photophobia, across an 8-week study period.

Conditions

Migraine Headache

Sleep

Photophobia

Study ID

NCT07476053

Start date

Mar 24, 2026

Status verified date

Apr, 2026

Completion date

Mar, 2027

Anticipated

Primary completion date

Mar, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Meet the International Classification of Headache Disorders, 3rd edition (2018) criteria for migraine, with or without aura or photosensitivity
  • Report experiencing more than 4 headache days per month and at least three migraine attacks per month
  • No other major health issues based on self-reported data
  • Able to read and communicate in English
  • Work in a private office space for at least six hours per day, four days per week

Exclusion Criteria:

  • Light therapy
  • Use light-altering devices (e.g., blue-blocking contact lenses or glasses)
  • Traveling out of town during the participation

Study Design

Enrollment

20 participants

Anticipated

Intervention Model

Single group

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: Optimized Lighting Intervention

All participants will complete a 4-week baseline observation period followed by a 4-week intervention period. During the baseline period, daily light exposure, sleep, and migraine characteristics will be monitored under natural conditions. During the intervention period, participants will use an optimized workplace lighting condition during working hours while continuing wearable monitoring and daily electronic surveys. Outcomes during the intervention period will be compared to baseline measurements within participants.

Interventions

Ambient Lighting Condition

Application of an optimized ambient lighting condition through placement of a dimmable LED floor lamp in participants' private workspaces to create a standardized workplace lighting environment during working hours. The floor lamp emits white light with a specified spectral distribution and intensity. Participants may adjust brightness for comfort. The lighting system is used solely to modify the ambient workplace lighting environment during the 4-week intervention period.

Primary outcome measure

  • Change in Monthly Migraine Days [ Time Frame: Baseline (Weeks 1-4) compared to Intervention (Weeks 5-8) ]

Central Contacts and Locations

Central contacts

Nina Sharp, PhD

480-965-6536nina.sharp@asu.edu

Locations

ASU DeSmart Lab

Recruiting

Tempe, Arizona, United States, 85281

Contacts

Nina Sharp, PhD

480-965-6536nina.sharp@asu.edu

More Information

Sponsor

Arizona State University

Last update posted

Apr 28, 2026

Last verified

Apr, 2026

Keywords

  • Migraine
  • Sleep
  • Lighting
  • Photophobia

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Arizona State University on 2026-04-28.