Recruiting

Observational Study

Sponsor:

University of Missouri-Columbia

Code:

NCT07489417

Conditions

Sleep

Blood Pressure

Eligibility Criteria

Sex: All

Age: 18 - 45

Healthy Volunteers: Accepted

Interventions

Sleep Restriction

Study Details

Brief summary:

The purpose of the research study is to examine the effects of shortened sleep on blood pressure.

Conditions

Sleep

Blood Pressure

Study ID

NCT07489417

Start date

Mar 4, 2026

Status verified date

Mar, 2026

Completion date

Aug, 2027

Anticipated

Primary completion date

Aug, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 45

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Healthy adult men and women
  • 18-45 years of age
  • BMI < 25 kg/m² (normal weight group) or ≥ 30 kg/m² (obesity group)
  • Non-pregnant, non-breastfeeding, and non-nicotine users
  • Self-reported history of normal sleep duration (7-9 hours/night) and bedtime prior to midnight
  • Premenopausal

Exclusion Criteria:

  • No acute or chronic conditions
  • Taking no medications known to affect sleep, autonomic, metabolic, or cardiovascular function
  • Self-reported history of irregular sleep
  • Self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological disease, stroke or neurovascular disease, bleeding/clotting disorders, sleep apnea or other sleep disorders, diabetes, history of alcoholism or substance abuse, major cardiovascular event or surgical procedure within the past three months, or hypertension

Study Design

Enrollment

45 participants

Anticipated

Allocation

Non randomized

Intervention Model

Crossover

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Sleep Restriction

You will be asked to shorten your sleep to four hours.

no intervention: Normal Sleep

You will be asked to sleep for 7-9 hours.

Interventions

Sleep Restriction

You will be asked to shorten your sleep to four hours.

Primary outcome measure

  • Mean Blood Pressure [ Time Frame: Baseline and during the last 1-minute of stress ]

Central Contacts and Locations

Central contacts

Jacqueline Limberg

1-573-882-2544limberglab@missouri.edu

Locations

University of Missouri

Recruiting

Columbia, Missouri, United States, 65211

Contacts

Jacqueline Limberg

573-882-2544limberglab@missouri.edu

Principal Investigator:

Jacqueline Limberg

More Information

Sponsor

University of Missouri-Columbia

Last update posted

Jul 28, 2026

Last verified

Mar, 2026

Keywords

  • Sleep
  • Blood pressure

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Missouri-Columbia on 2026-07-28.