Recruiting

Remote Exercise

Sponsor:

University of Colorado, Denver

Code:

NCT07498296

Conditions

PARKINSON DISEASE (Disorder)

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

High Intensity Resistance Exercise

Study Details

Brief summary:

Exercise is a primary intervention for symptom management in Parkinson's Disease (PD). However, challenges related to transportation, mobility, and socioeconomic factors often hinder consistent participation in exercise programs. To promote increased access and participation, remote exercise programs offer a promising solution.

The investigators previously showed that laboratory-based, high-intensity resistance exercise improves sleep efficiency in individuals with PD in a randomized, controlled, clinical trial. The investigators aim to adapt this protocol for remote delivery and to evaluate the usability of a remote sleep-monitoring device in people with Parkinson's Disease (PwP). Guided by the IDEAS framework for digital health intervention design, the investigators will modify the exercise protocol to ensure safety, accessibility, and fidelity in a home setting. Specific aims include: (1) assessing the adaptability of the HIRE protocol for remote implementation through participant acceptability ratings, adherence, exertion levels, and safety outcomes, (2) evaluating the usability of the Waveband sleep monitoring headband and adherence to night wear schedules, and 3) gather qualitative feedback through semi-structured interviews to understand participant perspectives on protocol design, session completion, and safety.

By integrating behavioral theory, participant engagement, and real-world constraints, this research will inform scalable, home-based interventions that are both effective and responsive to the lived experiences of PwP. The findings will lay the groundwork for future clinical trials and broader dissemination of remote therapeutic strategies in neurodegenerative care.

Conditions

PARKINSON DISEASE (Disorder)

Study ID

NCT07498296

Start date

Mar 5, 2026

Status verified date

May, 2026

Completion date

Nov 15, 2026

Anticipated

Primary completion date

Nov 15, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Currently residing in Colorado, USA
  • PD diagnosis per Movement Disorders Society Diagnostic Criteria
  • Requiring less than minimal assistance at home
  • Having internet access
  • Having a video-capable device

Exclusion Criteria:

  • Uncontrolled cardiovascular disease or pulmonary disease
  • Musculoskeletal injuries
  • Participation in Parkinson's Disease community exercise programs more than 3 days a week
  • Contraindication to physical activity as determined by the Physical Activity Readiness Questionnaire (PAR-Q)
  • Fall risk defined by requiring >20 seconds to complete the 5 times sit to stand test14 or high frequency of falls within the past year (≥ one fall per month)
  • Virtual Montreal Cognitive Assessment (MoCA) score ≥ 18 (performed at the eligibility visit)

Study Design

Enrollment

16 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Intervention

Interventions

High Intensity Resistance Exercise

5 upper and lower extremity resistance exercises for 10 repetitions for 3 sets; with additional body weight exercises in between sets

Primary outcome measure

  • Acceptability Survey [ Time Frame: Post intervention: Within one week after completion of the 3 exercise intervention ]
  • Semi Structured Interviews [ Time Frame: Post Intervention: Within one week after completion of the 3 exercise intervention ]

Central Contacts and Locations

Central contacts

Locations

University of Colorado Anschutz Medical Campus

Recruiting

Aurora, Colorado, United States, 80004-4159

Contacts

More Information

Sponsor

University of Colorado, Denver

Last update posted

May 15, 2026

Last verified

May, 2026

Keywords

  • exercise
  • remote exercise
  • parkinson's disease
  • feasibility
  • sleep monitoring

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Colorado, Denver on 2026-05-15.